Technology Process of C12H14O3
There total 3 articles about C12H14O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; disodium hydrogenphosphate; sodium dihydrogenphosphate;
In
water;
at 100 ℃;
for 8h;
Inert atmosphere;
DOI:10.1021/ja2041964
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1,4-diaza-bicyclo[2.2.2]octane / 144 h / 20 °C / Inert atmosphere
2.1: N-Bromosuccinimide; dimethylsulfide / dichloromethane / 1 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; sodium dihydrogenphosphate; disodium hydrogenphosphate / water / 8 h / 100 °C / Inert atmosphere
With
1,4-diaza-bicyclo[2.2.2]octane; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; disodium hydrogenphosphate; sodium dihydrogenphosphate; N-Bromosuccinimide; dimethylsulfide;
In
dichloromethane; water;
1.1: Baylis-Hillman reaction;
DOI:10.1021/ja2041964
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N-Bromosuccinimide; dimethylsulfide / dichloromethane / 1 h / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; sodium dihydrogenphosphate; disodium hydrogenphosphate / water / 8 h / 100 °C / Inert atmosphere
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; disodium hydrogenphosphate; sodium dihydrogenphosphate; N-Bromosuccinimide; dimethylsulfide;
In
dichloromethane; water;
DOI:10.1021/ja2041964
