N-[2-(phenyl)prop-2-en-1-yl]-N-benzylcarbonyl amide

Base Information

• Chemical Name: N-[2-(phenyl)prop-2-en-1-yl]-N-benzylcarbonyl amide
• CAS No.: 1447974-77-7
• Molecular Formula: C₁₇H₁₇NO₂
• Molecular Weight: 267.327
• Mol file: 1447974-77-7.mol

Synonyms:

Chemical Property of N-[2-(phenyl)prop-2-en-1-yl]-N-benzylcarbonyl amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-(phenyl)prop-2-en-1-yl]-N-benzylcarbonyl amide

There total 1 articles about N-[2-(phenyl)prop-2-en-1-yl]-N-benzylcarbonyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

3-phenylbut-3-enoic acid (5155-87-3) + sodium [(benzyloxy)carbonyl]chloroamide (91174-01-5) → N-[2-(phenyl)prop-2-en-1-yl]-N-benzylcarbonyl amide (1447974-77-7)

Guidance literature:

With iodine; sodium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h; regioselective reaction; Inert atmosphere;

DOI:10.1002/chem.201503298

Reference yield:

N-[2-(phenyl)prop-2-en-1-yl]-N-benzylcarbonyl amide (1447974-77-7) → 5-(chloromethyl)-5-phenyloxazolidin-2-one (1447974-69-7) + 5-(chloromethyl)-5-phenyloxazolidin-2-one (1447974-60-8)

Guidance literature:

With 1,3-dichloro-5,5-dimethylhydantoin; 1,4-bis(9-O-dihydroquinidine)phthalazine; In propan-1-ol; at -40 ℃; Temperature; Overall yield = 82 %; enantioselective reaction;

DOI:10.1002/chem.201300189

upstream raw materials:

3-phenylbut-3-enoic acid

sodium [(benzyloxy)carbonyl]chloroamide

Downstream raw materials:

5-(chloromethyl)-5-phenyloxazolidin-2-one

5-(chloromethyl)-5-phenyloxazolidin-2-one

Refernces