4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester

Base Information

Chemical Name:4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester
CAS No.:852807-93-3
Molecular Formula:C₂₈H₃₁F₃N₂O₄
Molecular Weight:516.56
Hs Code.:

4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester

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Chemical Property of 4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester

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Technology Process of 4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester

There total 3 articles about 4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106-24-1
Geraniol

: 852807-93-3
4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Heating

2: NH₄OAc / ethanol / Heating

With ammonium acetate; In ethanol; toluene; 2: Hantzsch reaction;
DOI:10.1016/j.tetlet.2005.03.057

Reference yield:

: 372-31-6
ethyl 4,4,4-trifluoroacetoacetate

: 852807-93-3
4-(3-Cyano-phenyl)-2-hydroxy-5-oxo-2-trifluoromethyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid (E)-3,7-dimethyl-octa-2,6-dienyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Heating

2: NH₄OAc / ethanol / Heating

With ammonium acetate; In ethanol; toluene; 2: Hantzsch reaction;
DOI:10.1016/j.tetlet.2005.03.057