Technology Process of Dimethyl (2S,3R)-3-benzyl-2-<<(1,1-dimethylethoxy)carbonyl>amino>-1,5-pentanedioate
There total 7 articles about Dimethyl (2S,3R)-3-benzyl-2-<<(1,1-dimethylethoxy)carbonyl>amino>-1,5-pentanedioate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 88 percent / tetra-n-butylammonium iodide, 3 M aq. K2CO3 / 16 h / Ambient temperature
2: 86 percent / TMSCl / tetrahydrofuran; diethyl ether / 1.) -40 deg C, 1 h, 2.) -40 deg C to r.t. over 3 h
3: 73 percent / p-toluenesulfonic acid / toluene / 4 h / Heating
4: K2CO3 / methanol / Ambient temperature
5: methanol; diethyl ether
6: pyridinium dichromate / dimethylformamide / Ambient temperature
7: methanol; diethyl ether
With
dipyridinium dichromate; chloro-trimethyl-silane; tetra-(n-butyl)ammonium iodide; potassium carbonate; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; diethyl ether; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00019a055
- Guidance literature:
-
Multi-step reaction with 4 steps
1: K2CO3 / methanol / Ambient temperature
2: methanol; diethyl ether
3: pyridinium dichromate / dimethylformamide / Ambient temperature
4: methanol; diethyl ether
With
dipyridinium dichromate; potassium carbonate;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jo00019a055
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridinium dichromate / dimethylformamide / Ambient temperature
2: methanol; diethyl ether
With
dipyridinium dichromate;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jo00019a055