cis-3-Methylcyclohexylamine

Base Information

• Chemical Name: cis-3-Methylcyclohexylamine
• CAS No.: 1193-16-4
• Molecular Formula: C7H15N
• Molecular Weight: 113.203
• Mol file: 1193-16-4.mol

Synonyms:(+-)-cis-3-methyl-cyclohexylamine;(1R,3S)-3-Methyl-cyclohexylamine;(+-)-cis-3-Methyl-cyclohexylamin;Cyclohexanamine, 3-methyl-, cis-;cis-3-methyl-cyclohexanamine;(+-)-cis-3-Amino-1-methyl-cyclohexan;3c-Amino-1c-methyl-cyclohexan;cis-3-Methylcyclohexylamin;

Chemical Property of cis-3-Methylcyclohexylamine

Chemical Property:

• Vapor Pressure: 4.101mmHg at 25°C
• Melting Point: -8.5°C (estimate)
• Refractive Index: 1.4538
• Boiling Point: 71 °C (48 mmHg)
• PSA: 26.02000
• Density: 0.8552
• LogP: 2.22410

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cis-3-Methylcyclohexylamine

There total 13 articles about cis-3-Methylcyclohexylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Methylacetanilide (537-92-8) → cis-3-methylcyclohexylamine (1193-16-4)

Guidance literature:

With ethanol; platinum; at 70 - 80 ℃; under 2280 Torr; Hydrogenation_.anschliessend man verseift durch Erhitzen mit konz. Salzsaeure auf 130-140grad;

DOI:10.1017/S0003598X00061378

Reference yield:

(+/-)-cis-3-methyl-cyclohexanecarboxylic acid (13293-59-9,73873-48-0,73873-49-1,77954-16-6,77954-17-7) → cis-3-methylcyclohexylamine (1193-16-4)

Guidance literature:

With sodium azide; sulfuric acid;

DOI:10.1021/ja01097a036

Reference yield:

1-amino-3-methylbenzene (108-44-1) → cis-3-methylcyclohexylamine (1193-16-4)

Guidance literature:

With hydrogen; acetic acid; platinum; at 23 - 26 ℃; under 2280 Torr;

upstream raw materials:

m-methylcyclohexanol

3-Methylacetanilide

(+/-)-cis-3-methyl-cyclohexanecarboxylic acid

formamide

Downstream raw materials:

(+/-)-dimethyl-(cis-3-methyl-cyclohexyl)-amine

Refernces

• 1、 Benkeser et al.. "-". . p. 854. Retrieved 1959.
• 2、 Tomkins, Patrick,Müller, Thomas E.. "Enhanced Selectivity in the Hydrogenation of Anilines to Cyclo-aliphatic Primary Amines over Lithium-Modified Ru/CNT Catalysts". . p. 1438 - 1445. Retrieved 2018/03/30.