C₂₅H₂₆N₂O₂S

Base Information

• Chemical Name: C₂₅H₂₆N₂O₂S
• CAS No.: 109356-00-5
• Molecular Formula: C₂₅H₂₆N₂O₂S
• Molecular Weight: 418.56
• Mol file: 109356-00-5.mol

Synonyms:

Chemical Property of C₂₅H₂₆N₂O₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₆N₂O₂S

There total 9 articles about C₂₅H₂₆N₂O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(17R,19E)-17,18-epoxy-1-methyl-cur-19-en-17-ol (24182-54-5) → C25H26N2O2S (109356-00-5)

Guidance literature:

Multi-step reaction with 8 steps

1: hydroxylamine-O-sulphonic acid / H₂O / Ambient temperature

2: Huenig's base / dimethylformamide

3: 1.) LDA, O₂, 2.) 1 M aq. SnCl₂, 1 M aq. HCl / 1.) THF, -78 deg C, 2.) 0 deg C

4: m-chloroperbenzoic acid / CHCl₃ / 0.5 h / Ambient temperature

5: 89 percent / potassium hydride, 18-crown-6 / 1,2-dimethoxy-ethane / 1 h / Ambient temperature

6: H₂ / Pd/C / ethyl acetate

7: HFx*pyridine / tetrahydrofuran

8: Bu₃P / tetrahydrofuran / 40 °C

With pyridine; hydrogenchloride; 18-crown-6 ether; tributylphosphine; hydrogen; oxygen; potassium hydride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; tin(ll) chloride; hydroxylamine-O-sulfonic acid; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; 1,2-dimethoxyethane; chloroform; water; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1039/c39860001564

Reference yield:

(17R,19E)-17,18-epoxy-cur-19-en-17-ol (466-85-3) → C25H26N2O2S (109356-00-5)

Guidance literature:

Multi-step reaction with 9 steps

1: NaBH₃CN / H₂O / Ambient temperature

2: hydroxylamine-O-sulphonic acid / H₂O / Ambient temperature

3: Huenig's base / dimethylformamide

4: 1.) LDA, O₂, 2.) 1 M aq. SnCl₂, 1 M aq. HCl / 1.) THF, -78 deg C, 2.) 0 deg C

5: m-chloroperbenzoic acid / CHCl₃ / 0.5 h / Ambient temperature

6: 89 percent / potassium hydride, 18-crown-6 / 1,2-dimethoxy-ethane / 1 h / Ambient temperature

7: H₂ / Pd/C / ethyl acetate

8: HFx*pyridine / tetrahydrofuran

9: Bu₃P / tetrahydrofuran / 40 °C

With pyridine; hydrogenchloride; 18-crown-6 ether; tributylphosphine; hydrogen; oxygen; potassium hydride; sodium cyanoborohydride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; tin(ll) chloride; hydroxylamine-O-sulfonic acid; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; 1,2-dimethoxyethane; chloroform; water; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1039/c39860001564

Reference yield:

C20H23N3O → C25H26N2O2S (109356-00-5)

Guidance literature:

Multi-step reaction with 7 steps

1: Huenig's base / dimethylformamide

2: 1.) LDA, O₂, 2.) 1 M aq. SnCl₂, 1 M aq. HCl / 1.) THF, -78 deg C, 2.) 0 deg C

3: m-chloroperbenzoic acid / CHCl₃ / 0.5 h / Ambient temperature

4: 89 percent / potassium hydride, 18-crown-6 / 1,2-dimethoxy-ethane / 1 h / Ambient temperature

5: H₂ / Pd/C / ethyl acetate

6: HFx*pyridine / tetrahydrofuran

7: Bu₃P / tetrahydrofuran / 40 °C

With pyridine; hydrogenchloride; 18-crown-6 ether; tributylphosphine; hydrogen; oxygen; potassium hydride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; tin(ll) chloride; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; 1,2-dimethoxyethane; chloroform; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1039/c39860001564

upstream raw materials:

diphenyldisulfane

C₁₉H₂₂N₂O₃

(17R,19E)-17,18-epoxy-1-methyl-cur-19-en-17-ol

(17R,19E)-17,18-epoxy-cur-19-en-17-ol