Technology Process of BrH*C28H25NO2
There total 9 articles about BrH*C28H25NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
at -70 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sodium hydroxide / dichloromethane; water / 20 °C
2.1: trichlorophosphate / acetonitrile / 5 h / Heating / reflux
2.2: 20 °C
3.1: sodium hydroxide / dichloromethane; water / 20 °C
4.1: hydrogenchloride / methanol; diethyl ether
5.1: dmap; triethylamine / DMF (N,N-dimethyl-formamide); dichloromethane / 0 - 20 °C
6.1: Resolution of racemate
7.1: sodium carbonate; triphenylphosphine / palladium diacetate / isopropyl alcohol / Heating / reflux
8.1: boron tribromide / dichloromethane / -70 - 20 °C
With
hydrogenchloride; dmap; sodium hydroxide; sodium carbonate; boron tribromide; triethylamine; triphenylphosphine; trichlorophosphate;
palladium diacetate;
In
methanol; DMF (N,N-dimethyl-formamide); diethyl ether; dichloromethane; water; isopropyl alcohol; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Resolution of racemate
2: sodium carbonate; triphenylphosphine / palladium diacetate / isopropyl alcohol / Heating / reflux
3: boron tribromide / dichloromethane / -70 - 20 °C
With
sodium carbonate; boron tribromide; triphenylphosphine;
palladium diacetate;
In
dichloromethane; isopropyl alcohol;
