C₂₃H₃₀FNO₆

Base Information

• Chemical Name: C₂₃H₃₀FNO₆
• CAS No.: 811867-38-6
• Molecular Formula: C₂₃H₃₀FNO₆
• Molecular Weight: 435.493
• Mol file: 811867-38-6.mol

Synonyms:

Chemical Property of C₂₃H₃₀FNO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₀FNO₆

There total 5 articles about C₂₃H₃₀FNO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C29H44FNO6Si (874335-97-4) → C23H30FNO6 (811867-38-6)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jm2007062

Reference yield:

2-bromo-5-fluorophenol (147460-41-1) → C23H30FNO6 (811867-38-6)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 55 °C / Inert atmosphere

2: copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; diisopropylamine / 1,4-dioxane; hexane / 60 °C / Inert atmosphere

3: platinum(IV) oxide; hydrogen / ethanol / 20 °C / Inert atmosphere

4: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

With platinum(IV) oxide; copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; diisopropylamine; potassium iodide; In tetrahydrofuran; 1,4-dioxane; ethanol; hexane; N,N-dimethyl-formamide; 2: Sonogashira coupling;

DOI:10.1021/jm2007062

Reference yield:

C14H22BrFO2Si (811867-36-4) → C23H30FNO6 (811867-38-6)

Guidance literature:

Multi-step reaction with 3 steps

1: copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; diisopropylamine / 1,4-dioxane; hexane / 60 °C / Inert atmosphere

2: platinum(IV) oxide; hydrogen / ethanol / 20 °C / Inert atmosphere

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

With platinum(IV) oxide; copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; tetrabutyl ammonium fluoride; hydrogen; diisopropylamine; In tetrahydrofuran; 1,4-dioxane; ethanol; hexane; 1: Sonogashira coupling;

DOI:10.1021/jm2007062

upstream raw materials:

C₁₄H₂₂BrFO₂Si

C₂₉H₄₄FNO₆Si

2-bromo-5-fluorophenol

Ddz-propargylamine