1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol

Base Information

Chemical Name:1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol
CAS No.:1272376-60-9
Molecular Formula:C₁₇H₂₀Cl₂O₄
Molecular Weight:359.249
Hs Code.:

Synonyms:

Suppliers and Price of 1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol

There total 1 articles about 1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-66-3,8013-54-5
chloroform

: 79241-07-9
(R)-4-((2S,3R)-3-(benzyloxy)-2,3-dihydrofuran-2-yl)-2,2-dimethyl-1,3-dioxolan

: 1272376-60-9
1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; In water; at 20 ℃; for 2.5h; air;
DOI:10.1039/c0ob00851f

Reference yield:

: 1272376-60-9
1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol

: 1272376-64-3
(3E,5R,6S,7R)-5-benzyloxy-3-chloro-6-hydroxy-7,8-O-isopropylideneocta-1,3-diene

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / 2 h / 80 °C

2.1: methanol; sodium / 0.5 h / 20 °C

3.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 1 h / -78 °C

3.2: -78 - 20 °C

With methanol; sodium; potassium hexamethylsilazane; acetic acid; In tetrahydrofuran; toluene; 3.1: Wittig reaction / 3.2: Wittig reaction;
DOI:10.1039/c0ob00851f

Reference yield:

: 1272376-60-9
1,4-anhydro-3-O-benzyl-2-deoxy-1,2-C-(dichloromethylene)-5,6-O-isopropylidene-D-glycero-D-glucohexitol

: (2S,3E,5R,6S,7R)-5-benzyloxy-3-chloro-1,2-epoxy-6-hydroxy-7,8-O-isopropylideneocta-3-ene

: 1272376-66-5
(2R,3E,5R,6S,7R)-5-benzyloxy-3-chloro-1,2-epoxy-6-hydroxy-7,8-O-isopropylideneocta-3-ene

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid / 2 h / 80 °C

2.1: methanol; sodium / 0.5 h / 20 °C

3.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 1 h / -78 °C

3.2: -78 - 20 °C

4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane; water / 48 h / 20 °C

With methanol; sodium; potassium hexamethylsilazane; acetic acid; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; water; toluene; 3.1: Wittig reaction / 3.2: Wittig reaction;
DOI:10.1039/c0ob00851f