20-Dihydroprogesterone Acetate

Base Information

• Chemical Name: 20-Dihydroprogesterone Acetate
• CAS No.: 5062-62-4
• Molecular Formula: C₂₃H₃₄O₃
• Molecular Weight: 358.521
• Mol file: 5062-62-4.mol

Synonyms:

Chemical Property of 20-Dihydroprogesterone Acetate

Chemical Property:

• Melting Point: 138-140 °C
• Boiling Point: 461.7±14.0 °C(Predicted)
• Density: 1.09±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

20-DihydroprogesteroneAcetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 20-Dihydroprogesterone acetate is an analogue of Progesterone (P755900), a steroid used in cardiovascular and menopausal studies. 20-Dihydroprogesterone Acetate (Progesterone EP Impurity E) is an analogue of Progesterone (P755900), a steroid used in cardiovascular and menopausal studies.

Technology Process of 20-Dihydroprogesterone Acetate

There total 5 articles about 20-Dihydroprogesterone Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 20β-Acetoxy-Δ4-pregnen-3-on (1474-70-0,4591-97-3,4591-98-4,5035-09-6,5062-62-4,36027-72-2)

Guidance literature:

aus III durch Acetylierung mit Ac2O/Py.;

DOI:10.1016/S0040-4020(01)92782-6

Reference yield:

→ 20α-Acetoxy-4-pregnen-3-on (1474-70-0,4591-97-3,4591-98-4,5035-09-6,5062-62-4,36027-72-2)

Guidance literature:

3-Methoxy-pregna-3.5-dien-20-on, 1.)Na/Isopropanol , 2.)Acetanhydrid/ Pyridin;

Reference yield:

pregna-5-ene-3β,20β-diol-20-acetate (1474-65-3) → 20βF-acetoxy-pregn-4-en-3-one (5062-62-4)

Guidance literature:

With nitrogen; aluminum isopropoxide; toluene; REagens 4:Cyclohexanon;

DOI:10.1002/hlca.19490320616

upstream raw materials:

pregna-5-ene-3β,20β-diol-20-acetate

vinyl acetate

20α-hydroxyprogesterone

Downstream raw materials:

pregna-1,4-diene-3,20-dione