Propanethioic acid, 2-chloro-, S-phenyl ester

Base Information

• Chemical Name: Propanethioic acid, 2-chloro-, S-phenyl ester
• CAS No.: 120346-68-1
• Molecular Formula: C9H9ClOS
• Molecular Weight: 200.689
• Mol file: 120346-68-1.mol

Synonyms:

Chemical Property of Propanethioic acid, 2-chloro-, S-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanethioic acid, 2-chloro-, S-phenyl ester

There total 5 articles about Propanethioic acid, 2-chloro-, S-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(E)-3-methyl-2-phenylsulphonyl-2-phenylthiooxirane (120346-61-4) → S-phenyl 2-chloro(thiopropanoate) (120346-68-1)

Guidance literature:

With lithium chloride; In acetone; for 5h; Ambient temperature;

DOI:10.1039/P19910003091

Reference yield:

1-(phenylsulfanyl)methyl phenyl sulfone (15296-86-3) → S-phenyl 2-chloro(thiopropanoate) (120346-68-1)

Guidance literature:

Multi-step reaction with 3 steps

2: 99 percent / lithium tert-butyl hydroperoxide / tetrahydrofuran; toluene / 0.5 h / -78 °C

3: 99 percent / lithium chloride / acetone / 5 h / Ambient temperature

With lithium tert-butyl hydroperoxide; lithium chloride; In tetrahydrofuran; acetone; toluene;

DOI:10.1039/P19910003091

Reference yield:

(E)-1-phenylsulphonyl-1-phenylthioprop-1-ene (120346-57-8) → S-phenyl 2-chloro(thiopropanoate) (120346-68-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / lithium tert-butyl hydroperoxide / tetrahydrofuran; toluene / 0.5 h / -78 °C

2: 99 percent / lithium chloride / acetone / 5 h / Ambient temperature

With lithium tert-butyl hydroperoxide; lithium chloride; In tetrahydrofuran; acetone; toluene;

DOI:10.1039/P19910003091

upstream raw materials:

(E)-3-methyl-2-phenylsulphonyl-2-phenylthiooxirane

bis(phenylthio)methane

phenyl phenylthiomethyl sulfoxide

1-(phenylsulfanyl)methyl phenyl sulfone

Refernces

• 1、 Hewkin, Cheryl T.,Jackson, Richard F. W.,Clegg, William. "PREPARATION OF 1-PHENYLSULPHONYL-1-PHENYLTHIO EPOXIDES: CONVENIENT PRECURSORS TO α-HALO S-PHENYL THIO ESTERS". . p. 4889 - 4892. Retrieved 2007/10/02.