4-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]benzenol

Base Information

• Chemical Name: 4-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]benzenol
• CAS No.: 318284-32-1
• Molecular Formula: C₁₈H₁₈N₂O
• Molecular Weight: 278.354
• DSSTox Substance ID: DTXSID501333344
• ChEMBL ID: CHEMBL1554385
• Mol file: 318284-32-1.mol

Synonyms:318284-32-1;4-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]phenol;4-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]benzenol;4-[(3,5-dimethyl-1-phenylpyrazol-4-yl)methyl]phenol;Bionet2_001546;MLS001165451;CHEMBL1554385;DTXSID501333344;HMS1368H05;HMS2873H11;AKOS005091871;SMR000549398;5C-014;4-(3,5-dimethyl-1-phenyl-1h-pyrazol-4-ylmethyl)phenol

Chemical Property of 4-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]benzenol

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 278.141913202
• Heavy Atom Count: 21
• Complexity: 321

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C(=NN1C2=CC=CC=C2)C)CC3=CC=C(C=C3)O

Technology Process of 4-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]benzenol

There total 1 articles about 4-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]benzenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethyl-1-phenyl-4-(chloromethyl)-1H-pyrazole (1152595-49-7) + phenol (108-95-2,27073-41-2) → 3,5-dimethyl-4-phenoxymethyl-1-phenyl-1H-pyrazole (1338826-74-6) + 4-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-ylmethyl)phenol (318284-32-1) + 2-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-ylmethyl)phenol (1338826-73-5)

Guidance literature:

phenol; With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; In 1,4-dioxane; at 70 ℃; for 0.5h;

3,5-dimethyl-1-phenyl-4-(chloromethyl)-1H-pyrazole; In 1,4-dioxane; for 13h;

DOI:10.1134/S1070363211080330

upstream raw materials:

3,5-dimethyl-1-phenyl-4-(chloromethyl)-1H-pyrazole

phenol