2-Trifluoroacetyl vinyl aMine

Base Information

• Chemical Name: 2-Trifluoroacetyl vinyl aMine
• CAS No.: 120417-45-0
• Molecular Formula: C4H4F3NO
• Molecular Weight: 139.077
• Mol file: 120417-45-0.mol

Synonyms:4-amino-1,1,1-trifluoro-3-buten-2-one;

Chemical Property of 2-Trifluoroacetyl vinyl aMine

Chemical Property:

• Refractive Index: 1.4675 (20℃)
• Boiling Point: 92-93℃ (15 Torr)
• PKA: 4.49±0.70(Predicted)
• PSA: 43.09000
• Density: 1.319±0.06 g/cm3(Predicted)
• LogP: 1.29050

Purity/Quality:

97% ^*data from raw suppliers

(Z)-4-Amino-1,1,1-trifluorobut-3-en-2-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Trifluoroacetyl vinyl aMine

There total 7 articles about 2-Trifluoroacetyl vinyl aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (59938-06-6) → 4-amino-1,1,1-trifluoro-3-buten-2-one (120417-45-0,184848-89-3)

Guidance literature:

With ammonium hydroxide; In acetonitrile; for 4h; Ambient temperature;

DOI:10.1016/S0040-4039(01)93334-9

Reference yield: 90.0%

ethyl β-(trifluoroacetyl)vinyl sulfide (127223-85-2,127223-98-7) → 4-amino-1,1,1-trifluoro-3-buten-2-one (120417-45-0,184848-89-3)

Guidance literature:

With ammonium hydroxide; In acetonitrile; Ambient temperature;

DOI:10.1016/S0040-4039(01)93334-9

Reference yield: 86.0%

4-ethoxy-1,1,1-trifluoro-3-butene-2-one (59938-06-6,17129-06-5) → 4-amino-1,1,1-trifluoro-3-butene-2-one (120417-45-0,184848-89-3)

Guidance literature:

With ammonia; at 20 ℃; for 3h;

upstream raw materials:

4-ethoxy-1,1,1-trifluoro-3-butene-2-one

(E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one

ethyl β-(trifluoroacetyl)vinyl sulfide

1,1,1-trifluoro-4-(phenylsulfonyl)but-3-ene-2,2-diol

Downstream raw materials:

(E)-4-(dimethylamino)-1,1,1-trifluorobut-3-en-2-one

1-trifluoromethyl-3-(phenylamino)prop-2-en-1-one

1,1,1-trifluoro-4-phthalimido-3-buten-2-one

(Z)-4-(N-methylamino)-1,1,1-trifluorobut-3-en-2-one