2,4-Hexadienoic acid, 5-(4-methoxyphenyl)-, (E,E)-

Base Information

• Chemical Name: 2,4-Hexadienoic acid, 5-(4-methoxyphenyl)-, (E,E)-
• CAS No.: 120554-24-7
• Molecular Formula: C13H14O3
• Molecular Weight: 218.252
• Mol file: 120554-24-7.mol

Synonyms:

Chemical Property of 2,4-Hexadienoic acid, 5-(4-methoxyphenyl)-, (E,E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Hexadienoic acid, 5-(4-methoxyphenyl)-, (E,E)-

There total 3 articles about 2,4-Hexadienoic acid, 5-(4-methoxyphenyl)-, (E,E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-methoxyphenyl)ethanone (100-06-1) → (E,E)-5-(4-methoxyphenyl)-2,4-hexadienoic acid (120554-24-7)

Guidance literature:

Multi-step reaction with 2 steps

2: 2.) NaOH / 1.) CH₂Cl₂, room temperature, 3 d, 2.) MeOH, H₂O, reflux, 30 min

With sodium hydroxide;

DOI:10.1021/jm00128a026

Reference yield:

(E)-3-(4-methoxyphenyl)but-2-enal (87580-60-7) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) → (E,E)-5-(4-methoxyphenyl)-2,4-hexadienoic acid (120554-24-7)

Guidance literature:

With sodium hydroxide; Yield given. Multistep reaction; 1.) CH₂Cl₂, room temperature, 3 d, 2.) MeOH, H₂O, reflux, 30 min;

DOI:10.1021/jm00128a026

Reference yield:

→ (E,E)-5-(4-methoxyphenyl)-2,4-hexadienoic acid (120554-24-7)

Guidance literature:

upstream raw materials:

(E)-3-(4-methoxyphenyl)but-2-enal

methyl (triphenylphosphoranylidene)acetate

1-(4-methoxyphenyl)ethanone

Downstream raw materials:

(E,E)-5-(4-methoxyphenyl)-2,4-hexadienoic acid 4-nitrophenyl ester

Refernces

• 1、 -. "Pentadieneamides". . . Retrieved 2008/06/13.