7,7-dibromo-1-phenyl-cis-norcarane

Base Information

• Chemical Name: 7,7-dibromo-1-phenyl-cis-norcarane
• CAS No.: 79929-90-1
• Molecular Formula: C₁₃H₁₄Br₂
• Molecular Weight: 330.062
• Mol file: 79929-90-1.mol

Synonyms:

Chemical Property of 7,7-dibromo-1-phenyl-cis-norcarane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7,7-dibromo-1-phenyl-cis-norcarane

There total 2 articles about 7,7-dibromo-1-phenyl-cis-norcarane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

Bromoform (75-25-2) + 1-phenyl-1-cyclohexane (827-52-1,5379-26-0) → 7,7-dibromo-1-phenyl-cis-norcarane (39165-19-0,79929-90-1)

Guidance literature:

With potassium tert-butylate; In hexane; for 1.5h; Ambient temperature;

DOI:10.1246/bcsj.54.2151

Reference yield:

Bromoform (75-25-2) + 1-Phenylcyclohexene (771-98-2) → 7,7-dibromo-1-phenyl-cis-norcarane (39165-19-0,79929-90-1)

Guidance literature:

With potassium tert-butylate; at 0 ℃;

DOI:10.1016/S0022-328X(99)00146-1

Reference yield:

7,7-dibromo-1-phenyl-cis-norcarane (39165-19-0,79929-90-1) → 1-phenylnorcarane-endo-7-carboxylic acid (79929-92-3,79981-36-5,111188-53-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) BuLi / 1.) THF, hexane, -95 deg C, 20 min, 2.) THF, hexane, from -95 deg C to RT

2: 72 mg / BuLi / tetrahydrofuran; hexane / 0.42 h / -78 °C

With n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1246/bcsj.54.2151

upstream raw materials:

Bromoform

1-phenyl-1-cyclohexane

1-Phenylcyclohexene

Downstream raw materials:

1-phenyl-1,3-cycloheptadiene

2-phenylcyclohepta-1,3-diene

exo-7-hydroxymethyl-1-phenylnorcarane

endo-7-hydroxymethyl-1-phenylnorcarane