3-[Tert-butyl(dimethyl)silyl]prop-2-yn-1-ol

Base Information

Chemical Name:3-[Tert-butyl(dimethyl)silyl]prop-2-yn-1-ol
CAS No.:120789-51-7
Molecular Formula:C9H18OSi
Molecular Weight:170.327
Hs Code.:
DSSTox Substance ID:DTXSID30373815
Nikkaji Number:J746.644G
Wikidata:Q82162157
Mol file:120789-51-7.mol

Synonyms:120789-51-7;3-tert-Butyldimethylsilyl-2-propyn-1-ol;3-[tert-butyl(dimethyl)silyl]prop-2-yn-1-ol;2-Propyn-1-ol, 3-[(1,1-dimethylethyl)dimethylsilyl]-;3-(tert-butyldimethylsilyl)prop-2-yn-1-ol;3-(tert-butyldimethylsilyl)-2-propyn-1-ol;SCHEMBL4447779;DTXSID30373815;BSFBEXRZAZEBTM-UHFFFAOYSA-N;AKOS006293485;3-t-butyl(dimethyl)silyl-2-propyn-1-ol;CS-0180905

Suppliers and Price of 3-[Tert-butyl(dimethyl)silyl]prop-2-yn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-TERT-BUTYLDIMETHYLSILYL-2-PROPYN-1-OL 97.00%
5G
$ 1212.75

AHH
3-tert-Butyldimethylsilyl-2-propyn-1-ol 97%
5g
$ 250.00

Total 10 raw suppliers

Chemical Property of 3-[Tert-butyl(dimethyl)silyl]prop-2-yn-1-ol

Chemical Property:

PSA：20.23000
LogP:2.02980
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:170.112691728
Heavy Atom Count:11
Complexity:187

Purity/Quality:

98%min ^*data from raw suppliers

3-TERT-BUTYLDIMETHYLSILYL-2-PROPYN-1-OL 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)C#CCO

Technology Process of 3-[Tert-butyl(dimethyl)silyl]prop-2-yn-1-ol

There total 12 articles about 3-[Tert-butyl(dimethyl)silyl]prop-2-yn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 135294-85-8
tert-butyldimethyl(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-yn-1-yl)silane

: 120789-51-7
3-tert-butyldimethylsilylpropargyl alcohol

Guidance literature:: With toluene-4-sulfonic acid; In methanol; Ambient temperature;
DOI:10.1016/0040-4020(96)00264-5

Reference yield: 93.0%

: 6089-04-9
3-(tetrahydropyran-2'-yloxy)propyne

: 18162-48-6
tert-butyldimethylsilyl chloride

: 120789-51-7
3-tert-butyldimethylsilylpropargyl alcohol

Guidance literature:: 3-(tetrahydropyran-2'-yloxy)propyne; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.333333h; Inert atmosphere;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;

With toluene-4-sulfonic acid; In methanol; at 23 ℃; for 2h; Inert atmosphere;
DOI:10.15227/orgsyn.076.0178

Reference yield: 54.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 107-19-7
propargyl alcohol

: 120789-51-7
3-tert-butyldimethylsilylpropargyl alcohol

Guidance literature:: propargyl alcohol; With ethylmagnesium bromide; In tetrahydrofuran;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; for 2h; Heating;
DOI:10.1002/hlca.200290002