N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide

Base Information

• Chemical Name: N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide
• CAS No.: 107321-97-1
• Molecular Formula: C₁₈H₁₇N₃O₄S
• Molecular Weight: 371.417
• Mol file: 107321-97-1.mol

Synonyms:

Chemical Property of N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide

There total 1 articles about N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sulphamoxole (729-99-7) + salicylaldehyde (90-02-8) → N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide (107321-97-1)

Guidance literature:

In ethanol; for 4h; Heating;

Reference yield: 69.0%

N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide (107321-97-1) + tin(ll) chloride → [SnCl2(HOC6H4CHNC6H4SO2NHC5H6ON)]

Guidance literature:

In tetrahydrofuran; soln. of equimolar amts. of anhyd. SnCl2 and ligand in THF stirred for 2 h under N2; evapd. in vac., solid washed with cyclohexane, dried in vac. at 40-50°C; elem. anal.;

Reference yield: 65.0%

dimethyltin dichloride (753-73-1) + N-(4,5-Dimethyl-oxazol-2-yl)-4-{[1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-benzenesulfonamide (107321-97-1) → [(CH3)2SnCl2(HOC6H4CHNC6H4SO2NHC5H6ON)]

Guidance literature:

In benzene; to soln. of Me2SnCl2 in dry C6H6 added equimolar amt. of ligand, refluxed under fractionating column for several h; evapd., solid washed with dry cyclohexane, dried in vac. at 40-50°C for 2-3 h; elem. anal.;

upstream raw materials:

sulphamoxole

salicylaldehyde