Technology Process of 9,10-Phenanthrenedione,
1,2,3,4,4a,10a-hexahydro-6,7-dimethoxy-1,1,4a-trimethyl-, cis-
There total 1 articles about 9,10-Phenanthrenedione,
1,2,3,4,4a,10a-hexahydro-6,7-dimethoxy-1,1,4a-trimethyl-, cis- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 82 percent / phosphate acid / toluene / 2 h / 100 °C
2: 91 percent / K2CO3 / acetone / 5 h / 20 °C
3: 85 percent / LiAlH4 / diethyl ether / 4 h / 20 °C
4: 55 percent / pyridine chromium trioxide chloride / CH2Cl2 / 4 h / 20 °C
5: 74.5 percent / n-BuLi / tetrahydrofuran / 6 h / 20 °C
6: 100 percent / H2 / Pd/C / diethyl ether / 0.5 h
7: boron trifluoride etherate / CH2Cl2 / 24 h / 20 °C
8: 66.5 percent / chromium trioxide; acetic acid / 50 °C
With
chromium(VI) oxide; lithium aluminium tetrahydride; n-butyllithium; phosphate acid; boron trifluoride diethyl etherate; hydrogen; potassium carbonate; acetic acid; pyridinium chlorochromate;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; dichloromethane; acetone; toluene;
DOI:10.1016/j.bmcl.2005.11.023
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 80 percent / t-BuOK / 2-methyl-propan-2-ol / 2 h / 20 °C
2: 85 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C
With
potassium tert-butylate; boron tribromide;
In
dichloromethane; tert-butyl alcohol;
DOI:10.1002/jccs.200200089
