10-O-Methoxymethyl SN-38

Base Information

Chemical Name:10-O-Methoxymethyl SN-38
CAS No.:1246815-54-2
Molecular Formula:C₂₄H₂₄N₂O₆
Molecular Weight:436.464
Hs Code.:
Mol file:1246815-54-2.mol

Synonyms:

Suppliers and Price of 10-O-Methoxymethyl SN-38

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
10-O-MethoxymethylSN-38
2.5mg
$ 165.00

American Custom Chemicals Corporation
10-O-METHOXYMETHYL-SN-38 95.00%
5MG
$ 499.93

Total 3 raw suppliers

Chemical Property of 10-O-Methoxymethyl SN-38

Chemical Property:

Solubility.:Chloroform, Dichloromethane, Methanol

Purity/Quality:

99% ^*data from raw suppliers

10-O-MethoxymethylSN-38 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Protected Irinotecan metabolite.

Technology Process of 10-O-Methoxymethyl SN-38

There total 1 articles about 10-O-Methoxymethyl SN-38 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 86639-52-3,110714-48-2,130144-34-2,113015-38-6,647852-82-2
7-ethyl-10-hydroxycamptothecin

: 107-30-2
chloromethyl methyl ether

: 1246815-54-2
SN-38

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 24h;

Reference yield: 96.0%

: 1246815-54-2
SN-38

: 7693-46-1
4-Nitrophenyl chloroformate

: 1310455-96-9
p-nitrophenyl-O-carbonyl-[20-(S)-O-7-ethyl-10-methoxymethyloxycamptothecin]

Guidance literature:: With dmap; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

: 1246815-54-2
SN-38

: 1310456-01-9
C₄₃H₅₀N₄O₁₀

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / dichloromethane / 1 h / 20 °C / Inert atmosphere

2: N,N-dimethyl-formamide / 3 h / 20 °C

With dmap; In dichloromethane; N,N-dimethyl-formamide;