N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance

Base Information

• Chemical Name: N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance
• CAS No.: 59830-58-9
• Molecular Formula: C₂₈H₃₀N₂O₅
• Molecular Weight: 474.557
• Mol file: 59830-58-9.mol

Synonyms:

Chemical Property of N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance

There total 4 articles about N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance (5276-63-1,17257-53-3,17257-55-5,59830-58-9)

Guidance literature:

With diethyl ether; phosphorus pentachloride; Behandeln des Reaktionsprodukts mit DL-Phenylalanin-aethylester in Aethylacetat;

DOI:10.1021/ja01846a064

Reference yield:

benzyl (1-hydrazinyl-1-oxo-3-phenylpropan-2-yl)carbamate (21887-86-5) → N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance (5276-63-1,17257-53-3,17257-55-5,59830-58-9)

Guidance literature:

With hydrogenchloride; acetic acid; sodium nitrite; Behandeln des Reaktionsprodukts mit DL-Phenylalanin-aethylester in Aether;

DOI:10.1007/BF00902822

Reference yield:

chloroformic acid ethyl ester (541-41-3) + Z-DL-Phe-OH (3588-57-6) → N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine ethyl ester; optically inactive substance (5276-63-1,17257-53-3,17257-55-5,59830-58-9)

Guidance literature:

With 1,4-dioxane; tributyl-amine; anschliessend Behandeln mit DL-Phenylalanin-aethylester-hydrochlorid;

upstream raw materials:

benzyl (1-hydrazinyl-1-oxo-3-phenylpropan-2-yl)carbamate

chloroformic acid ethyl ester

Z-DL-Phe-OH

Downstream raw materials:

N-(N-benzyloxycarbonyl-phenylalanyl)-phenylalanine