benzyl DL-2-amino-5-phosphonopentanoate

Base Information

• Chemical Name: benzyl DL-2-amino-5-phosphonopentanoate
• CAS No.: 113811-53-3
• Molecular Formula: C₁₂H₁₈NO₅P
• Molecular Weight: 287.252

Synonyms:

Chemical Property of benzyl DL-2-amino-5-phosphonopentanoate

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of benzyl DL-2-amino-5-phosphonopentanoate

There total 1 articles about benzyl DL-2-amino-5-phosphonopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

APV (76326-31-3) + benzyl alcohol (100-51-6,185532-71-2) → benzyl DL-2-amino-5-phosphonopentanoate (113811-53-3)

Guidance literature:

With thionyl chloride; for 18h; Ambient temperature;

DOI:10.1021/jm00402a012

Reference yield:

4-amino-4-deoxy-N10-formylpteroic acid (89043-75-4) + benzyl DL-2-amino-5-phosphonopentanoate (113811-53-3) → N-(4-amino-4-deoxypteroyl)-DL-2-amino-5-phosphonopentanoic acid (113811-43-1)

Guidance literature:

With triethylamine; isobutyl chloroformate; Yield given. Multistep reaction; 1) DMF; 2) DMF;

DOI:10.1021/jm00402a012

upstream raw materials:

APV

benzyl alcohol

Downstream raw materials:

N-(4-amino-4-deoxypteroyl)-DL-2-amino-5-phosphonopentanoic acid

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