(6-Chloro-5-methylpyridin-3-yl)methanamine

Base Information

• Chemical Name: (6-Chloro-5-methylpyridin-3-yl)methanamine
• CAS No.: 1256824-90-4
• Molecular Formula: C₇H₉ClN₂
• Molecular Weight: 156.615
• DSSTox Substance ID: DTXSID80694183
• Wikidata: Q82623203
• Mol file: 1256824-90-4.mol

Synonyms:(6-chloro-5-methylpyridin-3-yl)methanamine;1256824-90-4;(6-CHLORO-5-METHYLPYRIDIN-3-YL)METHYLAMINE;SCHEMBL1912301;DTXSID80694183;MFCD18254322;AB74569;CS-0194481;E91391;EN300-1964880;1-(6-CHLORO-5-METHYLPYRIDIN-3-YL)METHANAMINE

Chemical Property of (6-Chloro-5-methylpyridin-3-yl)methanamine

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 156.0454260
• Heavy Atom Count: 10
• Complexity: 108

Purity/Quality:

97% ^*data from raw suppliers

(6-Chloro-5-methylpyridin-3-yl)methanamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=CN=C1Cl)CN

Technology Process of (6-Chloro-5-methylpyridin-3-yl)methanamine

There total 3 articles about (6-Chloro-5-methylpyridin-3-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

tert-butyl (6-chloro-5-methylpyridin-3-yl)methylcarbamate → (6-chloro-5-methylpyridin-3-yl)methanamine (1256824-90-4)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2016.09.041

Reference yield: 83.0%

C13H18ClNO2 → (6-chloro-5-methylpyridin-3-yl)methanamine (1256824-90-4)

Guidance literature:

In dichloromethane; trifluoroacetic acid; at 20 ℃; for 3h;

Reference yield:

6-chloro-5-methylpyridine-3-carboxaldehyde (176433-43-5) → (6-chloro-5-methylpyridin-3-yl)methanamine (1256824-90-4)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid; triethylsilane / acetonitrile / 24 h / 20 °C

2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

With triethylsilane; trifluoroacetic acid; In dichloromethane; acetonitrile;

DOI:10.1016/j.bmc.2016.09.041

upstream raw materials:

6-chloro-5-methylpyridine-3-carboxaldehyde

Downstream raw materials:

N-((3-methyl-2'-(trifluoromethyl)-2,4'-bipyridin-5-yl)methyl)-4-(pyrazin-2-yl)benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1256824-90-4 (6-chloro-5-methylpyridin-3-yl)methanamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send