6-Chloro-5-methylpyridine-3-carbaldehyde

Base Information

Chemical Name:6-Chloro-5-methylpyridine-3-carbaldehyde
CAS No.:176433-43-5
Molecular Formula:C7H6 Cl N O
Molecular Weight:155.584
Hs Code.:2933399990
European Community (EC) Number:886-644-0
DSSTox Substance ID:DTXSID30599391
Wikidata:Q82495270
Mol file:176433-43-5.mol

Synonyms:6-Chloro-5-methylnicotinaldehyde;176433-43-5;6-chloro-5-methylpyridine-3-carbaldehyde;2-Chloro-5-formyl-3-methylpyridine;3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-;MFCD11520655;6-Chloro-5-methylpyridine-3-carboxaldehyde;SCHEMBL248753;DTXSID30599391;UGZVEYLUBVYKAD-UHFFFAOYSA-N;BCP08525;BHA43343;6-chloro-3-formyl-5-methyl-pyridine;AKOS005072450;AB64236;CS-W000612;ED-0221;6-chloro-5-methyl-3-pyridinecarbaldehyde;DA-19278;SY067101;EN300-107717;A852140;J-011192;J-518595

Suppliers and Price of 6-Chloro-5-methylpyridine-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-5-methylnicotinaldehyde
500mg
$ 130.00

SynQuest Laboratories
6-Chloro-5-methylnicotinaldehyde
1 g
$ 228.00

SynQuest Laboratories
6-Chloro-5-methylnicotinaldehyde
500 mg
$ 173.00

Matrix Scientific
6-Chloro-5-methylnicotinaldehyde >95%
5g
$ 197.00

Matrix Scientific
6-Chloro-5-methylnicotinaldehyde >95%
1g
$ 54.00

Matrix Scientific
6-Chloro-5-methylnicotinaldehyde >95%
500mg
$ 35.00

Frontier Specialty Chemicals
2-Chloro-5-formyl-3-methylpyridine 98%
25g
$ 600.00

Frontier Specialty Chemicals
2-Chloro-5-formyl-3-methylpyridine 98%
5g
$ 200.00

Frontier Specialty Chemicals
2-Chloro-5-formyl-3-methylpyridine 98%
1g
$ 50.00

Crysdot
6-Chloro-5-methylnicotinaldehyde 95+%
1g
$ 105.00

Total 29 raw suppliers

Chemical Property of 6-Chloro-5-methylpyridine-3-carbaldehyde

Chemical Property:

Melting Point:51-53oC
Boiling Point:269.2±35.0 °C(Predicted)
PKA:-1.24±0.10(Predicted)
PSA：29.96000
Density:1.269±0.06 g/cm3(Predicted)
LogP:1.85590
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:155.0137915
Heavy Atom Count:10
Complexity:129

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-5-methylnicotinaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CN=C1Cl)C=O

Technology Process of 6-Chloro-5-methylpyridine-3-carbaldehyde

There total 8 articles about 6-Chloro-5-methylpyridine-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.6%

: 4394-85-8
4-morpholinecarboxaldehyde

: 29241-60-9
5-bromo-2-chloro-3-methylpyridine

: 176433-43-5
6-chloro-5-methylpyridine-3-carboxaldehyde

Guidance literature:: 5-bromo-2-chloro-3-methylpyridine; With isopropylmagnesium chloride; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

4-morpholinecarboxaldehyde; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield: 69.0%

: 887707-21-3
(6-chloro-5-methylpyridin-3-yl)methanol

: 176433-43-5
6-chloro-5-methylpyridine-3-carboxaldehyde

Guidance literature:: With chromium (VI) oxide; In dichloromethane; at 40 ℃;

Reference yield: 66.0%

: 59782-89-7
2-Chloro-5-iodo-3-methylpyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 176433-43-5
6-chloro-5-methylpyridine-3-carboxaldehyde

Guidance literature:: 2-Chloro-5-iodo-3-methylpyridine; With n-butyllithium; In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h;

N,N-dimethyl-formamide; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 1h;

With water;
DOI:10.1021/jm401808n