5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate

Base Information

• Chemical Name: 5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate
• CAS No.: 1374694-38-8
• Molecular Formula: C₁₉H₁₆ClNO₆
• Molecular Weight: 389.792
• Mol file: 1374694-38-8.mol

Synonyms:

Chemical Property of 5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate

There total 3 articles about 5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methoxyphenylacetic acid (104-01-8) → 5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate (1374694-38-8)

Guidance literature:

Multi-step reaction with 3 steps

1: boron trifluoride diethyl etherate / 80 °C / Inert atmosphere

2: boron trifluoride diethyl etherate; methanesulfonyl chloride / 50 - 80 °C / Inert atmosphere

3: pyridine / diethyl ether / 0 - 20 °C

With pyridine; boron trifluoride diethyl etherate; methanesulfonyl chloride; In diethyl ether; 1: Friedel-Crafts acylation;

DOI:10.1016/j.bmc.2012.03.012

Reference yield:

2,4,6-trihydroxy-4'-methoxydeoxybenzoin (15485-66-2) → 5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate (1374694-38-8)

Guidance literature:

Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate; methanesulfonyl chloride / 50 - 80 °C / Inert atmosphere

2: pyridine / diethyl ether / 0 - 20 °C

With pyridine; boron trifluoride diethyl etherate; methanesulfonyl chloride; In diethyl ether;

DOI:10.1016/j.bmc.2012.03.012

Reference yield:

3,5-dihydroxyphenol (108-73-6) → 5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 2-chloroethylcarbamate (1374694-38-8)

Guidance literature:

Multi-step reaction with 3 steps

1: boron trifluoride diethyl etherate / 80 °C / Inert atmosphere

2: boron trifluoride diethyl etherate; methanesulfonyl chloride / 50 - 80 °C / Inert atmosphere

3: pyridine / diethyl ether / 0 - 20 °C

With pyridine; boron trifluoride diethyl etherate; methanesulfonyl chloride; In diethyl ether; 1: Friedel-Crafts acylation;

DOI:10.1016/j.bmc.2012.03.012

upstream raw materials:

4-Methoxyphenylacetic acid

3,5-dihydroxyphenol

2,4,6-trihydroxy-4'-methoxydeoxybenzoin