3-fluoro-5-hydrazinylpyridine

Base Information

• Chemical Name: 3-fluoro-5-hydrazinylpyridine
• CAS No.: 1318760-55-2
• Molecular Formula: C₅H₆FN₃
• Molecular Weight: 127.121
• Mol file: 1318760-55-2.mol

Synonyms:

Chemical Property of 3-fluoro-5-hydrazinylpyridine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-Fluoro-5-hydrazinylpyridine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-fluoro-5-hydrazinylpyridine

There total 2 articles about 3-fluoro-5-hydrazinylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

5-fluoropyridin-3-amine (210169-05-4) → 3-fluoro-5-hydrazinylpyridine (1318760-55-2)

Guidance literature:

5-fluoropyridin-3-amine; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 1.11h;

With hydrogenchloride; tin(ll) chloride; In water; at 0 - 20 ℃; for 23.55h;

Reference yield:

3,5-difluoropyridine (71902-33-5) → 3-fluoro-5-hydrazinylpyridine (1318760-55-2)

Guidance literature:

With hydrazine hydrate; In isopropyl alcohol; at 100 ℃; for 12h;

upstream raw materials:

5-fluoropyridin-3-amine

3,5-difluoropyridine

Refernces

• 1、 -. "PYRAZOLE COMPOUNDS SUBSTITUTED WITH HETEROARYL AND PHARMACEUTICAL USE THEREOF". Paragraph 0262-0265. . Retrieved 2019/11/11.