Technology Process of 4-(cyclopropylmethoxy)aniline
There total 6 articles about 4-(cyclopropylmethoxy)aniline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
ethyl acetate;
at 20 ℃;
for 2h;
under 2327.23 Torr;
- Guidance literature:
-
With
magnesium; ethylene dibromide;
In
tetrahydrofuran;
Inert atmosphere;
With
C10H17NO;
In
tetrahydrofuran; toluene;
at -78 ℃;
for 2h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 75 percent / K2CO3 / dimethylformamide / 16 h / 20 °C
2: 52 percent / ethanol / tin(II)chloride dihydrate / 24 h / Heating
With
ethanol; potassium carbonate;
tin(ll) chloride;
In
N,N-dimethyl-formamide;
DOI:10.1021/jm058026u