(S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

Base Information

Chemical Name:(S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide
CAS No.:416898-04-9
Molecular Formula:C₄₀H₆₀N₁₀O₆
Molecular Weight:776.98
Hs Code.:

(S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

Synonyms:

Suppliers and Price of (S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

There total 6 articles about (S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 172980-45-9
valylalanine methyl ester isocyanate

: 416898-04-9
(S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

Guidance literature:: Multi-step reaction with 5 steps

1: 99 percent / CH₂Cl₂ / 1 h

2: 75 percent / 1,2-dichloro-ethane / 36 h / Heating

3: 100 percent / TFA / CH₂Cl₂ / 1.5 h

4: 84 percent / methanol / 168 h

5: 0.227 g / methanol / 0.75 h

With trifluoroacetic acid; In methanol; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/S0040-4020(01)01092-4

Reference yield:

: 174497-02-0
[2-(2-Phenylamino-ethylamino)-ethyl]-carbamic acid tert-butyl ester

: 416898-04-9
(S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

Guidance literature:: Multi-step reaction with 5 steps

1: 99 percent / CH₂Cl₂ / 1 h

2: 75 percent / 1,2-dichloro-ethane / 36 h / Heating

3: 100 percent / TFA / CH₂Cl₂ / 1.5 h

4: 84 percent / methanol / 168 h

5: 0.227 g / methanol / 0.75 h

With trifluoroacetic acid; In methanol; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/S0040-4020(01)01092-4

Reference yield:

: 416898-00-5
(S)-2-{(S)-2-[3-(2-tert-Butoxycarbonylamino-ethyl)-3-(2-phenylamino-ethyl)-ureido]-3-methyl-butyrylamino}-propionic acid methyl ester

: 416898-04-9
(S)-2-{(S)-2-[3-(2-{1-[2-(2-Cyano-ethylamino)-ethyl]-3-[(S)-2-methyl-1-((S)-1-methylcarbamoyl-ethylcarbamoyl)-propyl]-ureido}-ethyl)-3-phenyl-ureido]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methylamide

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / 1,2-dichloro-ethane / 36 h / Heating

2: 100 percent / TFA / CH₂Cl₂ / 1.5 h

3: 84 percent / methanol / 168 h

4: 0.227 g / methanol / 0.75 h

With trifluoroacetic acid; In methanol; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/S0040-4020(01)01092-4