Benzenemethanol, 3-(2-quinolinylmethoxy)-

Base Information

Chemical Name:Benzenemethanol, 3-(2-quinolinylmethoxy)-
CAS No.:123226-28-8
Molecular Formula:C17H15NO2
Molecular Weight:265.312
Hs Code.:
ChEMBL ID:CHEMBL5174405
DSSTox Substance ID:DTXSID20562610
Wikidata:Q82446851
Mol file:123226-28-8.mol

Synonyms:123226-28-8;(3-(quinolin-2-ylmethoxy)phenyl)methanol;CHEMBL5174405;CAY10789;Benzenemethanol, 3-(2-quinolinylmethoxy)-;SCHEMBL4848317;DTXSID20562610;FARMNDXIOAHJMF-UHFFFAOYSA-N;3-(2-quinolylmethoxy)benzyl alcohol;BDBM50596187;3-(2-quinolinylmethoxy)benzyl alcohol;3-(Quinol-2-ylmethoxy)benzyl alcohol;3-(2-quinolinylmethyloxy)benzyl alcohol;3-(Quinolin-2-ylmethoxy)benzyl alcohol;2-(3-hydroxymethylphenoxy)methylquinoline;HY-147086;[3-(Quinolin-2-ylmethoxy)-phenyl]-methanol;{3-[(Quinolin-2-yl)methoxy]phenyl}methanol

Suppliers and Price of Benzenemethanol, 3-(2-quinolinylmethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzenemethanol, 3-(2-quinolinylmethoxy)-

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:265.110278721
Heavy Atom Count:20
Complexity:297

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC(=N2)COC3=CC=CC(=C3)CO

Technology Process of Benzenemethanol, 3-(2-quinolinylmethoxy)-

There total 4 articles about Benzenemethanol, 3-(2-quinolinylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 123226-28-8
2-(3-hydroxymethylphenoxy)methylquinoline

Guidance literature:

Reference yield: 60.0%

: 119515-00-3
3-(2-Quinolinylmethoxy)benzoic acid methyl ester

: 123226-28-8
2-(3-hydroxymethylphenoxy)methylquinoline

Guidance literature:: With diisobutylaluminium hydride; In tetrahydrofuran; at 0 ℃; for 8h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.1c01078

Reference yield:

: 19575-07-6
quinoline-2-carboxylic acid methyl ester

: 123226-28-8
2-(3-hydroxymethylphenoxy)methylquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: diisobutylaluminium hydride / tetrahydrofuran / 8 h / 0 °C / Inert atmosphere

2: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 12 h / 0 °C / Inert atmosphere

3: diisobutylaluminium hydride / tetrahydrofuran / 8 h / 0 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; diisobutylaluminium hydride; triphenylphosphine; In tetrahydrofuran; 2: |Mitsunobu Displacement;
DOI:10.1021/acs.jmedchem.1c01078