Cyclohexanamine, N-[(2-methoxyphenyl)methylene]-

Base Information

• Chemical Name: Cyclohexanamine, N-[(2-methoxyphenyl)methylene]-
• CAS No.: 123334-93-0
• Molecular Formula: C14H19NO
• Molecular Weight: 217.311
• DSSTox Substance ID: DTXSID20444740
• Nikkaji Number: J276.784H
• Mol file: 123334-93-0.mol

Synonyms:Cyclohexanamine, N-[(2-methoxyphenyl)methylene]-;123334-93-0;SCHEMBL3982235;DTXSID20444740;BWRTYSRMCAZULB-UHFFFAOYSA-N;N-Cyclohexyl-2-methoxybenzenemethanimine;N-(2-Methoxyphenyl)methylidenecyclohexylamine

Chemical Property of Cyclohexanamine, N-[(2-methoxyphenyl)methylene]-

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 217.146664230
• Heavy Atom Count: 16
• Complexity: 221

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1C=NC2CCCCC2

Technology Process of Cyclohexanamine, N-[(2-methoxyphenyl)methylene]-

There total 3 articles about Cyclohexanamine, N-[(2-methoxyphenyl)methylene]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(2-methoxyphenyl)methanol (612-16-8) + cyclohexylamine (108-91-8,157973-60-9) → Cyclohexyl-[1-(2-methoxy-phenyl)-meth-(E)-ylidene]-amine (123334-93-0)

Guidance literature:

With calcium nitride; N,N'-bis(salicylidene)-1,2-cyclohexanediaminomanganese(III) chloride; In toluene; for 48h; Reflux;

DOI:10.1039/c8sc03969k

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) + ortho-anisaldehyde (135-02-4) → (E)-N-cyclohexyl-1-(2-methoxyphenyl)methanimine (123334-93-0)

Guidance literature:

In benzene; for 0.5h; Heating;

DOI:10.1021/jo00290a022

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) + ortho-anisaldehyde (135-02-4) → Cyclohexyl-[1-(2-methoxy-phenyl)-meth-(E)-ylidene]-amine (123334-93-0)

Guidance literature:

With acetic acid; In ethanol;

DOI:10.1016/j.tetlet.2008.08.056

upstream raw materials:

cyclohexylamine

ortho-anisaldehyde

(2-methoxyphenyl)methanol

Downstream raw materials:

C₂₆H₃₂N₂O₅

N-[(2-methoxyphenyl)methyl]cyclohexanamine