N⁴-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-<5'-amino-N⁴-benzoyl-2',5'-dideoxycytidylyl-(3'-5'-carbamoyl)>2-5'-amino-N⁴-benzoyl-2',5'-dideoxycytidine

Base Information

• Chemical Name: N⁴-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-<5'-amino-N⁴-benzoyl-2',5'-dideoxycytidylyl-(3'-5'-carbamoyl)>2-5'-amino-N⁴-benzoyl-2',5'-dideoxycytidine
• CAS No.: 109979-05-7
• Molecular Formula: C₈₇H₈₂N₁₆O₂₀
• Molecular Weight: 1671.7

Synonyms:

Chemical Property of N⁴-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-<5'-amino-N⁴-benzoyl-2',5'-dideoxycytidylyl-(3'-5'-carbamoyl)>2-5'-amino-N⁴-benzoyl-2',5'-dideoxycytidine

Chemical Property:

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Safty Information:

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MSDS Files:

Useful:

Technology Process of N⁴-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-<5'-amino-N⁴-benzoyl-2',5'-dideoxycytidylyl-(3'-5'-carbamoyl)>2-5'-amino-N⁴-benzoyl-2',5'-dideoxycytidine

There total 1 articles about N⁴-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-<5'-amino-N⁴-benzoyl-2',5'-dideoxycytidylyl-(3'-5'-carbamoyl)>2-5'-amino-N⁴-benzoyl-2',5'-dideoxycytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitrophenyl N4-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-5'-amino-N4-benzoyl-2',5'-dideoxycytidine 3'-carbonate (109979-02-4) + [(2R,3S,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl]-carbamic acid (2R,3S,5R)-2-aminomethyl-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester; compound with toluene-4-sulfonic acid (109979-04-6) → N4-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-<5'-amino-N4-benzoyl-2',5'-dideoxycytidylyl-(3'-5'-carbamoyl)>2-5'-amino-N4-benzoyl-2',5'-dideoxycytidine (109979-05-7)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; Yield given;

DOI:10.1021/jo00228a010

Reference yield:

toluene-4-sulfonic acid (104-15-4) + N4-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-<5'-amino-N4-benzoyl-2',5'-dideoxycytidylyl-(3'-5'-carbamoyl)>2-5'-amino-N4-benzoyl-2',5'-dideoxycytidine (109979-05-7) → C67H66N16O19*C7H8O3S (109979-07-9)

Guidance literature:

With acetic acid; In methanol; for 5h; Ambient temperature;

DOI:10.1021/jo00228a010

upstream raw materials:

4-nitrophenyl N⁴-benzoyl-2',5'-dideoxy-5'-(4''-monomethoxytrityl)aminocytidylyl-(3'-5''-carbamoyl)-5'-amino-N⁴-benzoyl-2',5'-dideoxycytidine 3'-carbonate

[(2R,3S,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl]-carbamic acid (2R,3S,5R)-2-aminomethyl-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester; compound with toluene-4-sulfonic acid

Downstream raw materials:

C₆₇H₆₆N₁₆O₁₉*C₇H₈O₃S

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