S-methyl phenyldiazothioacetate

Base Information

• Chemical Name: S-methyl phenyldiazothioacetate
• CAS No.: 144043-54-9
• Molecular Formula: C₉H₈N₂OS
• Molecular Weight: 192.241
• Mol file: 144043-54-9.mol

Synonyms:

Chemical Property of S-methyl phenyldiazothioacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-methyl phenyldiazothioacetate

There total 2 articles about S-methyl phenyldiazothioacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-methyl 2-phenylethanethioate (5925-74-6) → S-methyl phenyldiazothioacetate (144043-54-9)

Guidance literature:

With dmap; 4-toluenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In diethyl ether; for 60h; Ambient temperature;

DOI:10.1021/jo00050a019

Reference yield:

phenylacetyl chloride (103-80-0) → S-methyl phenyldiazothioacetate (144043-54-9)

Guidance literature:

Multi-step reaction with 2 steps

2: p-toluenesulfonyl azide, 1,8-diazobicyclo<5.4.0>undec-7-ene (DBU), 4-(N,N-dimethylamino)pyridine / diethyl ether / 60 h / Ambient temperature

With dmap; 4-toluenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In diethyl ether;

DOI:10.1021/jo00050a019

Reference yield:

S-methyl phenyldiazothioacetate (144043-54-9) → hydroxyphenylthioacetic acid S-methyl ester (21504-28-9) + <α-(methylthio)>benzenacetic acid (55843-16-8)

Guidance literature:

With perchloric acid; at 25 ℃; Rate constant; Product distribution; Mechanism; ionic strength 0.10 M (NaClO₄); reaction in D₂O: isotope effect; reaction in aq. carboxylic acid buffer solutions;

DOI:10.1021/jo00062a005

upstream raw materials:

S-methyl 2-phenylethanethioate

phenylacetyl chloride

Downstream raw materials:

hydroxyphenylthioacetic acid S-methyl ester

<α-(methylthio)>benzenacetic acid