8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one

Base Information

• Chemical Name: 8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one
• CAS No.: 79056-26-1
• Molecular Formula: C₅₃H₆₀O₁₁
• Molecular Weight: 873.053
• Mol file: 79056-26-1.mol

Synonyms:

Chemical Property of 8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one

There total 2 articles about 8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

trans-2,2',4,4'-tetramethoxy-3'-prenylchalcone (76489-56-0) + (E)-2-(2,4-dimethoxyphenyl)-5,7-dimethoxy-3-(3-methylbut-2-en-1-yl)-8-(3-methylbuta-1,3-dien-1-yl)-4H-chromen-4-one (79004-61-8) → 8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one (76851-98-4,79056-26-1,79056-47-6) + 8-[(1R,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one (79056-47-6)

Guidance literature:

With 2,6-di-tert-butyl-4-methyl-phenol; In toluene; at 170 ℃; for 81h;

DOI:10.1016/S0040-4039(01)90496-4

Reference yield:

albanin G (76472-87-2) + dimethyl sulfate (77-78-1) → 8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one (76851-98-4,79056-26-1,79056-47-6)

Guidance literature:

DOI:10.1246/cl.1980.1577

Reference yield:

8-[(1S,5R,6S)-6-[2,4-Dimethoxy-3-(3-methyl-but-2-enyl)-benzoyl]-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one (76851-98-4,79056-26-1,79056-47-6) → tetrahydrokuwanon C tetramethyl ether (68754-21-2)

Guidance literature:

Multi-step reaction with 2 steps

2: H₂ / Pt

With hydrogen; platinum;

DOI:10.1246/cl.1980.1577

upstream raw materials:

trans-2,2',4,4'-tetramethoxy-3'-prenylchalcone

(E)-2-(2,4-dimethoxyphenyl)-5,7-dimethoxy-3-(3-methylbut-2-en-1-yl)-8-(3-methylbuta-1,3-dien-1-yl)-4H-chromen-4-one

albanin G

dimethyl sulfate

Downstream raw materials:

trans-2,2',4,4'-tetramethoxy-3'-prenylchalcone

2-(2,4-Dimethoxy-phenyl)-5,7-dimethoxy-8-((E)-3-methyl-buta-1,3-dienyl)-3-(3-methyl-but-2-enyl)-chromen-4-one

tetrahydrokuwanon C tetramethyl ether