4-Chloroquinazolin-2-amine

Base Information

Chemical Name:4-Chloroquinazolin-2-amine
CAS No.:124309-74-6
Molecular Formula:C8H6ClN3
Molecular Weight:179.60600
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30439920
Wikidata:Q82256028
Mol file:124309-74-6.mol

Synonyms:4-chloroquinazolin-2-amine;124309-74-6;2-Quinazolinamine, 4-chloro-;2-AMINO-4-CHLOROQUINAZOLINE;SCHEMBL8128619;DTXSID30439920;FFAZODWQFAWXCO-UHFFFAOYSA-N;MFCD10697893;AKOS006303181;AB60762;PS-17842;CS-0329194;FT-0660423;F15722

Suppliers and Price of 4-Chloroquinazolin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloroquinazolin-2-amine
100mg
$ 350.00

Labseeker
2-QUINAZOLINAMINE,4-CHLORO- 95
2g
$ 1283.00

Crysdot
4-Chloroquinazolin-2-amine 95+%
250mg
$ 880.00

Chemenu
4-Chloroquinazolin-2-amine 95%
1g
$ 1262.00

American Custom Chemicals Corporation
4-CHLOROQUINAZOLIN-2-AMINE 95.00%
5MG
$ 504.71

Alichem
4-Chloroquinazolin-2-amine
1g
$ 1323.00

Alichem
4-Chloroquinazolin-2-amine
250mg
$ 583.20

Total 14 raw suppliers

Chemical Property of 4-Chloroquinazolin-2-amine

Chemical Property:

Boiling Point:403.4±37.0 °C(Predicted)
PKA:3.79±0.10(Predicted)
PSA：52.53000
Density:1.445±0.06 g/cm3(Predicted)
LogP:1.79550
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:179.0250249
Heavy Atom Count:12
Complexity:164

Purity/Quality:

97% ^*data from raw suppliers

4-Chloroquinazolin-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=NC(=N2)N)Cl

Technology Process of 4-Chloroquinazolin-2-amine

There total 3 articles about 4-Chloroquinazolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 20198-19-0
2-amino-4(3H)-quinazolinone

: 124309-74-6
4-chloroquinazolin-2-amine

Guidance literature:: In trichlorophosphate;

Reference yield:

: 20198-19-0
2-aminoquinazolin-4(1H)-one

: 124309-74-6
4-chloroquinazolin-2-amine

Guidance literature:: With N,N-dimethyl-aniline; trichlorophosphate; for 0.75h; Heating;
DOI:10.1021/jm00014a027

Reference yield:

: 134-20-3
2-carbomethoxyaniline

: 124309-74-6
4-chloroquinazolin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium methylate / methanol; water; butan-1-ol

2: trichlorophosphate

With sodium methylate; In methanol; water; trichlorophosphate; butan-1-ol;