(3S)-N-Methyl-1-benzylpyrrolidine-3alpha-methanamine

Base Information

Chemical Name:(3S)-N-Methyl-1-benzylpyrrolidine-3alpha-methanamine
CAS No.:303111-42-4
Molecular Formula:C₁₃H₂₀N₂
Molecular Weight:204.315
Hs Code.:
DSSTox Substance ID:DTXSID601207130
Nikkaji Number:J1.387.833A

Synonyms:DTXSID601207130;(3S)-N-Methyl-1-benzylpyrrolidine-3alpha-methanamine;(3S)-N-Methyl-1-(phenylmethyl)-3-pyrrolidinemethanamine;303111-42-4

Suppliers and Price of (3S)-N-Methyl-1-benzylpyrrolidine-3alpha-methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (3S)-N-Methyl-1-benzylpyrrolidine-3alpha-methanamine

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:204.162648646
Heavy Atom Count:15
Complexity:175

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CNCC1CCN(C1)CC2=CC=CC=C2
Isomeric SMILES:CNC[C@@H]1CCN(C1)CC2=CC=CC=C2

Technology Process of (3S)-N-Methyl-1-benzylpyrrolidine-3alpha-methanamine

There total 2 articles about (3S)-N-Methyl-1-benzylpyrrolidine-3alpha-methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 303111-41-3
(R)-(1-benzyl-pyrrolidin-3-ylmethyl)-carbamic acid tert-butyl ester

: 303111-42-4
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-methyl-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Heating;
DOI:10.1016/S0960-894X(00)00405-4

Reference yield:

: 229323-07-3
(R)-C-(1-benzyl-pyrrolidin-3-yl)-methylamine

: 303111-42-4
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-methyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / CH₂Cl₂ / 20 °C

2: LiAlH₄ / tetrahydrofuran / 4 h / Heating

With lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane; 1: Acylation / 2: Reduction;
DOI:10.1016/S0960-894X(00)00405-4