2-Chloro-3-(piperidin-1-yl)quinoxaline

Base Information

Chemical Name:2-Chloro-3-(piperidin-1-yl)quinoxaline
CAS No.:32998-26-8
Molecular Formula:C₁₃H₁₄ClN₃
Molecular Weight:247.727
Hs Code.:2933990090
NSC Number:41971
DSSTox Substance ID:DTXSID30285449
Wikidata:Q82020822
Mol file:32998-26-8.mol

Synonyms:2-chloro-3-(piperidin-1-yl)quinoxaline;32998-26-8;2-chloro-3-piperidin-1-ylquinoxaline;2-chloro-3-piperidinoquinoxaline;2-chloro-3-(1-piperidyl)quinoxaline;2-chloro-3-(1-piperidinyl)quinoxaline;NSC41971;Oprea1_804525;DTXSID30285449;MFCD00105617;NSC 41971;NSC-41971;AKOS000269705;CS-0222341;EN300-110877;AI-204/31689061;F3398-1739;Z992946850

Suppliers and Price of 2-Chloro-3-(piperidin-1-yl)quinoxaline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2-Chloro-3-(piperidin-1-yl)quinoxaline
10g
$ 1337.00

AK Scientific
2-Chloro-3-(piperidin-1-yl)quinoxaline
5g
$ 934.00

Total 6 raw suppliers

Chemical Property of 2-Chloro-3-(piperidin-1-yl)quinoxaline

Chemical Property:

Vapor Pressure:4.6E-06mmHg at 25°C
Melting Point:67 °C
Boiling Point:382.8°Cat760mmHg
PKA:3.66±0.59(Predicted)
Flash Point:185.3°C
PSA：29.02000
Density:1.275g/cm³
LogP:3.33850
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:247.0876252
Heavy Atom Count:17
Complexity:255

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-3-(piperidin-1-yl)quinoxaline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C2=NC3=CC=CC=C3N=C2Cl

Technology Process of 2-Chloro-3-(piperidin-1-yl)quinoxaline

There total 7 articles about 2-Chloro-3-(piperidin-1-yl)quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 110-89-4
piperidine

: 2213-63-0
2,3-dichloroquinoxaline

: 32998-26-8
2-Chlor-3-piperidino-chinoxalin

Guidance literature:: In acetonitrile; at 80 ℃; for 5h;
DOI:10.1016/j.tet.2016.08.067

Reference yield:

: 2213-63-0
2,3-dichloroquinoxaline

: 32998-26-8
2-Chlor-3-piperidino-chinoxalin

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / ammonia / various solvent(s) / 4 h / 140 °C

2: 83 percent / trifluoromethanesulfonic anhydride, dimethylsulfoxide

3: 1.) m-chloroperbenzoic acid; 2.) ozon

4: 0.25 h / Ambient temperature; variation of solvents and reagents

With ammonia; ozone; dimethyl sulfoxide; trifluoromethanesulfonic acid anhydride; 3-chloro-benzenecarboperoxoic acid; In various solvent(s);

Reference yield:

: 15804-19-0
2,3-dihydroxyquinoxaline

: 32998-26-8
2-Chlor-3-piperidino-chinoxalin

Guidance literature:: Multi-step reaction with 5 steps

1: 66 percent / phosphoryl chloride, phosphorus pentachloride / 8 h / Heating

2: 75 percent / ammonia / various solvent(s) / 4 h / 140 °C

3: 83 percent / trifluoromethanesulfonic anhydride, dimethylsulfoxide

4: 1.) m-chloroperbenzoic acid; 2.) ozon

5: 0.25 h / Ambient temperature; variation of solvents and reagents

With phosphorus pentachloride; ammonia; ozone; dimethyl sulfoxide; trifluoromethanesulfonic acid anhydride; 3-chloro-benzenecarboperoxoic acid; trichlorophosphate; In various solvent(s);