Methyl 2-formylisonicotinate

Base Information

Chemical Name:Methyl 2-formylisonicotinate
CAS No.:125104-34-9
Molecular Formula:C8H7NO3
Molecular Weight:165.148
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70599491
Wikidata:Q82495380
Mol file:125104-34-9.mol

Synonyms:Methyl 2-formylisonicotinate;125104-34-9;METHYL 2-FORMYLPYRIDINE-4-CARBOXYLATE;4-Pyridinecarboxylic acid, 2-formyl-, methyl ester;MFCD14582033;Methyl2-formylisonicotinate;SCHEMBL582011;DTXSID70599491;FLXVRBSKKVMMQQ-UHFFFAOYSA-N;BCP15433;AKOS016002597;CS-W006156;DS-3519;SB21354;DA-16842;SY105765

Suppliers and Price of Methyl 2-formylisonicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-Formylisonicotinate
10mg
$ 45.00

Medical Isotopes, Inc.
Methyl2-formylisonicotinate 95+%
1 g
$ 780.00

Crysdot
Methyl2-formylisonicotinate 98%
1g
$ 287.00

Crysdot
Methyl2-formylisonicotinate 98%
5g
$ 881.00

Crysdot
Methyl2-formylisonicotinate 98%
10g
$ 1436.00

Chemenu
methyl2-formylisonicotinate 98%
10g
$ 1356.00

Chemenu
methyl2-formylisonicotinate 98%
1g
$ 271.00

American Custom Chemicals Corporation
METHYL-2-FORMYLISONICOTINATE 95.00%
5MG
$ 504.26

Ambeed
Methyl2-formylisonicotinate 98%
250mg
$ 139.00

Ambeed
Methyl2-formylisonicotinate 98%
100mg
$ 25.00

Total 31 raw suppliers

Chemical Property of Methyl 2-formylisonicotinate

Chemical Property:

Boiling Point:274.1±25.0 °C(Predicted)
PKA:1.07±0.10(Predicted)
PSA：56.26000
Density:1.249±0.06 g/cm3(Predicted)
LogP:0.68070
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:165.042593085
Heavy Atom Count:12
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-Formylisonicotinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=NC=C1)C=O

Technology Process of Methyl 2-formylisonicotinate

There total 4 articles about Methyl 2-formylisonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 58481-17-7
methyl 2-(hydroxymethyl)pyridine-4-carboxylate

: 125104-34-9
methyl 2-formylpyridine-4-carboxylate

Guidance literature:: methyl 2-(hydroxymethyl)pyridine-4-carboxylate; With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2.5h;

With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃; for 0.25h;

Reference yield:

: 25658-36-0
pyridine-2,4-dicarboxylic acid dimethyl ester

: 125104-34-9
methyl 2-formylpyridine-4-carboxylate

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -60 ℃; for 1.33333h;
DOI:10.1135/cccc19980199

Reference yield:

: 2459-09-8
4-pyridinecarboxylic acid, methyl ester

: 125104-34-9
methyl 2-formylpyridine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium persulfate; sulfuric acid / water / 0.67 h / Reflux

2: Dess-Martin periodane / dichloromethane / 2.5 h / 20 °C

With ammonium persulfate; sulfuric acid; Dess-Martin periodane; In dichloromethane; water;