6-(Bromomethyl)quinolin-2(1H)-one

Base Information

Chemical Name:6-(Bromomethyl)quinolin-2(1H)-one
CAS No.:103702-29-0
Molecular Formula:C₁₀H₈BrNO
Molecular Weight:238.084
Hs Code.:
DSSTox Substance ID:DTXSID20537464
Wikidata:Q82412456
Mol file:103702-29-0.mol

Synonyms:6-(BROMOMETHYL)QUINOLIN-2(1H)-ONE;103702-29-0;6-(bromomethyl)-1H-quinolin-2-one;SCHEMBL15230239;DTXSID20537464;MFCD28662599;SY295227

Suppliers and Price of 6-(Bromomethyl)quinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-(Bromomethyl)quinolin-2(1H)-one

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:236.97893
Heavy Atom Count:13
Complexity:239

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=O)N2)C=C1CBr

Technology Process of 6-(Bromomethyl)quinolin-2(1H)-one

There total 3 articles about 6-(Bromomethyl)quinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 103702-27-8
6-(hydroxymethyl)quinolin-2(1H)-one

: 103702-29-0
6-Bromomethyl-1H-quinolin-2-one

Guidance literature:: With hydrogen bromide;
DOI:10.1248/cpb.33.3775

Reference yield:

: 90800-31-0
2-oxo-1,2-dihydroquinoline-6-carbaldehyde

: 103702-29-0
6-Bromomethyl-1H-quinolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / methanol

2: 49 percent / 47 percent hydrobromic acid

With hydrogen bromide; In methanol;
DOI:10.1248/cpb.33.3775

Reference yield:

: 103702-41-6
6-(1-hydroxy-2-isopropylaminopropyl)-2-(1H)-quinolinone

: 103702-29-0
6-Bromomethyl-1H-quinolin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / sodium metaperiodate / H₂O; dimethylformamide / 2.5 h / 60 - 70 °C

2: 54 percent / methanol

3: 49 percent / 47 percent hydrobromic acid

With sodium periodate; hydrogen bromide; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1248/cpb.33.3775