2,4-Thiazolidinedione, 5-[(4-fluorophenyl)sulfonyl]-

Base Information

Chemical Name:2,4-Thiazolidinedione, 5-[(4-fluorophenyl)sulfonyl]-
CAS No.:125518-56-1
Molecular Formula:C9H6FNO4S2
Molecular Weight:275.281
Hs Code.:
DSSTox Substance ID:DTXSID00441176
Nikkaji Number:J294.237B
ChEMBL ID:CHEMBL33126
Mol file:125518-56-1.mol

Synonyms:125518-56-1;2,4-Thiazolidinedione, 5-[(4-fluorophenyl)sulfonyl]-;CHEMBL33126;SCHEMBL6787966;DTXSID00441176;5-(4-Fluorophenylsulfonyl)thiazolidine-2,4-dione

Suppliers and Price of 2,4-Thiazolidinedione, 5-[(4-fluorophenyl)sulfonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,4-Thiazolidinedione, 5-[(4-fluorophenyl)sulfonyl]-

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:274.97222818
Heavy Atom Count:17
Complexity:436

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1F)S(=O)(=O)C2C(=O)NC(=O)S2

Technology Process of 2,4-Thiazolidinedione, 5-[(4-fluorophenyl)sulfonyl]-

There total 1 articles about 2,4-Thiazolidinedione, 5-[(4-fluorophenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 371-42-6
4-Fluorothiophenol

: 125518-56-1
5-[(4-fluorophenyl)sulfonyl]-2,4-thiazolidinedione

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / Na₂CO₃ / H₂O / 16 h / 0 °C

2: 81 percent / 30percent aq. H₂O₂, glac. AcOH / 3 h / 60 °C

With dihydrogen peroxide; sodium carbonate; acetic acid; In water;
DOI:10.1021/jm9706168

Reference yield:

: 173019-89-1
[3-(3,5-Bis(fluoro)phenyl)-prop-2-ynyl]-bromide

: 125518-56-1
5-[(4-fluorophenyl)sulfonyl]-2,4-thiazolidinedione

: 173019-82-4
1-(3-bromo-prop-1-ynyl)-4-chloro-benzene

: 5-[3-(4-Chloro-phenyl)-prop-2-ynyl]-5-(4-fluoro-benzenesulfonyl)thiazolidine-2,4-dione

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; mineral oil;

Reference yield:

: 14064-13-2
(1-methylcyclohexyl)methanol

: 125518-56-1
5-[(4-fluorophenyl)sulfonyl]-2,4-thiazolidinedione

: 125518-59-4
5-<<4-<(1-methylcyclohexyl)methoxy>phenyl>sulfonyl>-2,4-thiazolidinedione

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 55 deg C, 30 min, 2.) 55 deg C, 3 h;
DOI:10.1021/jm00167a022