(1,8-naphthyridin-2-yl)methanol

Base Information

Chemical Name:(1,8-naphthyridin-2-yl)methanol
CAS No.:125902-27-4
Molecular Formula:C9H8N2O
Molecular Weight:160.17300
Hs Code.:
Mol file:125902-27-4.mol

Synonyms:2-(Hydroxymethyl)-1,8-naphthyridine;(1,8-naphthyridin-2-yl)methanol;1,8-Naphthyridine-2-methanol;

Suppliers and Price of (1,8-naphthyridin-2-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1,8-Naphthyridine-2-methanol 97.00%
25G
$ 7910.00

AccelPharmtech
1,8-Naphthyridine-2-methanol 97.00%
5G
$ 4220.00

AccelPharmtech
1,8-Naphthyridine-2-methanol 97.00%
1G
$ 2460.00

Total 4 raw suppliers

Chemical Property of (1,8-naphthyridin-2-yl)methanol

Chemical Property:

PSA：46.01000
LogP:1.12210

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1,8-Naphthyridine-2-methanol 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1,8-naphthyridin-2-yl)methanol

There total 4 articles about (1,8-naphthyridin-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 125902-26-3
methyl 1,8-naphthyridine-2-carboxylate

: 125902-27-4
2-(Hydroxymethyl)-1,8-naphthyridine

Guidance literature:: With sodium trimethoxyborohydride; In tetrahydrofuran; dichloromethane; at 25 ℃; for 1h;
DOI:10.1021/jo00296a051

Reference yield:

: 215523-34-5
1,8-naphthyridine-2-carboxylic acid

: 125902-27-4
2-(Hydroxymethyl)-1,8-naphthyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 12 h / Heating

2: 59 percent / NaBH(OMe)3 / tetrahydrofuran; CH₂Cl₂ / 1 h / 25 °C

With sodium trimethoxyborohydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00296a051

Reference yield:

: 125902-24-1
2-(Trichloromethyl)-1,8-naphthyridine

: 125902-27-4
2-(Hydroxymethyl)-1,8-naphthyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 85percent H₃PO₄ / 3 h / 140 °C

2: 12 h / Heating

3: 59 percent / NaBH(OMe)3 / tetrahydrofuran; CH₂Cl₂ / 1 h / 25 °C

With phosphoric acid; sodium trimethoxyborohydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00296a051