125902-26-3Relevant articles and documents
Iridium complexes with ligands of 1,8-Naphthyridine-2-carboxylic acid derivatives-preparation and catalysis
Hsu, Yen-Pin,Li, Ming,Liu, Shiuh-Tzung,Liu, Yi-Hung,Peng, Shie-Ming
, (2020/10/02)
Complexation of 1,8-naphthyridine(Np)-2-carboxylic derivatives L1-L3 [L1 = Np-2-COOH, L2 = Np-2-CONH2, L3 = Np-2-CONHCH2Py] with [Ir(COD)(μ-OMe)]2 yielded the corresponding complexes [Ir(COD)(Ln)] (1~3, n = 1~3, respectively). The potential tridentate L3 behaves as a bidentate donor in the complex 3. Treatment of L1 with [Ir(COD)Cl]2 under nitrogen atmosphere gave a Ir(III) hydride complex [Ir(COD)(L1)HCl] (4). However, carrying out the reaction in the presence of oxygen rendered a Ir(III) dichloride species [Ir(COD)(L1)Cl2] (5). All these complexes were characterized by spectroscopic analyses and X-ray single crystal determination. Catalytic activity of iridium complexes in amination of amines with alcohols was screened. It appears that iridium amido complexes 2 and 3 show excellent catalytic activity on amination of anilines with alcohols in the presence of Cs2CO3 at 120 °C.
ANTIBACTERIAL AGENTS
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Page/Page column 38, (2010/11/25)
Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
