N-isopropyl-5-methoxy-2-(2-pyridinyl)-4-pyrimidinamine

Base Information

Chemical Name:N-isopropyl-5-methoxy-2-(2-pyridinyl)-4-pyrimidinamine
CAS No.:338771-57-6
Molecular Formula:C₁₃H₁₆N₄O
Molecular Weight:244.296
Hs Code.:
DSSTox Substance ID:DTXSID301185703
ChEMBL ID:CHEMBL578675
Mol file:338771-57-6.mol

Synonyms:N-isopropyl-5-methoxy-2-(2-pyridinyl)-4-pyrimidinamine;GNF-Pf-107;338771-57-6;Oprea1_175536;MLS000692222;CHEMBL578675;SCHEMBL1701097;5-methoxy-N-propan-2-yl-2-pyridin-2-ylpyrimidin-4-amine;BDBM435154;DTXSID301185703;HMS2655I17;US10584134, Example 2-1;AKOS005085261;2J-352S;US10584134, Example 2-15;US10584134, Example 2-16;US10584134, Example 2-17;US10584134, Example 2-18;US10584134, Example 2-19;US10584134, Example 2-20;US10584134, Example 2-21;US10584134, Example 2-22;SMR000333890;5-Methoxy-N-(1-methylethyl)-2-(2-pyridinyl)-4-pyrimidinamine;5-methoxy-N-(propan-2-yl)-2-(pyridin-2-yl)pyrimidin-4-amine;N-ISOPROPYL-5-METHOXY-2-(PYRIDIN-2-YL)PYRIMIDIN-4-AMINE

Suppliers and Price of N-isopropyl-5-methoxy-2-(2-pyridinyl)-4-pyrimidinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-ISOPROPYL-5-METHOXY-2-(2-PYRIDINYL)-4-PYRIMIDINAMINE 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
N-ISOPROPYL-5-METHOXY-2-(2-PYRIDINYL)-4-PYRIMIDINAMINE 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
N-ISOPROPYL-5-METHOXY-2-(2-PYRIDINYL)-4-PYRIMIDINAMINE 95.00%
1MG
$ 647.61

Total 1 raw suppliers

Chemical Property of N-isopropyl-5-methoxy-2-(2-pyridinyl)-4-pyrimidinamine

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:244.13241115
Heavy Atom Count:18
Complexity:249

Purity/Quality:: N-ISOPROPYL-5-METHOXY-2-(2-PYRIDINYL)-4-PYRIMIDINAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)NC1=NC(=NC=C1OC)C2=CC=CC=N2

Technology Process of N-isopropyl-5-methoxy-2-(2-pyridinyl)-4-pyrimidinamine

There total 5 articles about N-isopropyl-5-methoxy-2-(2-pyridinyl)-4-pyrimidinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 321432-82-0
4-chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine

: 75-31-0
isopropylamine

: 338771-57-6
Isopropyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-amine

Guidance literature:: at 32 ℃;

Reference yield:

: 100-70-9,1232006-36-8
2-Cyanopyridine

: 338771-57-6
Isopropyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-amine

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium methylate / methanol / 20 °C

1.2: 5 h / Reflux

2.1: methanol / 5.5 h / 10 - 63 °C

2.2: pH 4 - 5

3.1: trichlorophosphate / 1.5 h / Reflux

4.1: 32 °C

With sodium methylate; trichlorophosphate; In methanol;

Reference yield:

: pyridine-2-carboxamidine hydrochloride

: 338771-57-6
Isopropyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: methanol / 5.5 h / 10 - 63 °C

1.2: pH 4 - 5

2.1: trichlorophosphate / 1.5 h / Reflux

3.1: 32 °C

With trichlorophosphate; In methanol;