Thiobenzoic acid S-(3-{3-[2-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-ethyl]-3H-diazirin-3-yl}-propyl) ester

Base Information

• Chemical Name: Thiobenzoic acid S-(3-{3-[2-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-ethyl]-3H-diazirin-3-yl}-propyl) ester
• CAS No.: 172949-95-0
• Molecular Formula: C₂₄H₃₂N₂O₆S
• Molecular Weight: 476.594
• Mol file: 172949-95-0.mol

Synonyms:

Chemical Property of Thiobenzoic acid S-(3-{3-[2-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-ethyl]-3H-diazirin-3-yl}-propyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Thiobenzoic acid S-(3-{3-[2-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-ethyl]-3H-diazirin-3-yl}-propyl) ester

There total 2 articles about Thiobenzoic acid S-(3-{3-[2-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-ethyl]-3H-diazirin-3-yl}-propyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

thiobenzoic acid potassium salt (28170-13-0) + 8-Azi-6,7,8,9,10-pentadesoxy-1,2:3,4-di-O-isopropyliden-11-O-tosyl-α-D-galacto-undecopyranose-(1,5) (124382-39-4) → Thiobenzoic acid S-(3-{3-[2-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-ethyl]-3H-diazirin-3-yl}-propyl) ester (172949-95-0)

Guidance literature:

In acetone; Ambient temperature;

DOI:10.1016/0008-6215(95)00145-J

Reference yield:

8-Azi-6,7,8,9,10-pentadesoxy-1,2:3,4-di-O-isopropyliden-α-D-galacto-undecopyranose-(1,5) (124225-22-5) → Thiobenzoic acid S-(3-{3-[2-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-ethyl]-3H-diazirin-3-yl}-propyl) ester (172949-95-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / 4-dimethylaminopyridine / CH₂Cl₂ / Ambient temperature

2: 95 percent / acetone / Ambient temperature

With dmap; In dichloromethane; acetone;

DOI:10.1016/0008-6215(95)00145-J

upstream raw materials:

thiobenzoic acid potassium salt

8-Azi-6,7,8,9,10-pentadesoxy-1,2:3,4-di-O-isopropyliden-11-O-tosyl-α-D-galacto-undecopyranose-(1,5)

8-Azi-6,7,8,9,10-pentadesoxy-1,2:3,4-di-O-isopropyliden-α-D-galacto-undecopyranose-(1,5)