(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester

Base Information

Chemical Name:(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester
CAS No.:125971-93-9
Molecular Formula:C11H19NO4
Molecular Weight:229.276
Hs Code.:
Mol file:125971-93-9.mol

Synonyms:Hexanoic acid, 6-cyano-3,5-dihydroxy-, 1,1-dimethylethyl ester, [R-(R*,R*)]-;[R-(R*,R*)]-tert-Butyl 6-cyano-3,5-dihydroxyhexanoate;tert-Butyl (3R,5R)-6-cyano-3,5-dihydroxyhexanoate;

Suppliers and Price of (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoicAcidtert-ButylEster
100mg
$ 505.00

Biosynth Carbosynth
(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic acid tert-butyl ester
100 mg
$ 460.00

Biosynth Carbosynth
(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic acid tert-butyl ester
50 mg
$ 270.00

Biosynth Carbosynth
(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic acid tert-butyl ester
25 mg
$ 150.00

Biosynth Carbosynth
(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic acid tert-butyl ester
10 mg
$ 75.00

Biosynth Carbosynth
(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic acid tert-butyl ester
5 mg
$ 50.00

American Custom Chemicals Corporation
(3R,5R)-6-CYANO-3,5-DIHYDROXY-HEXANOIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 504.65

Total 36 raw suppliers

Chemical Property of (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.48
Boiling Point:410.244 °C at 760 mmHg
PKA:13.49±0.20(Predicted)
Flash Point:201.909 °C
PSA：90.55000
Density:1.131 g/cm³
LogP:0.74378
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoicAcidtert-ButylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Intermediate in the production of Atorvastatin.

Technology Process of (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester

There total 26 articles about (3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 125988-01-4
tert-butyl (5R)-6-cyano-5-hydroxy-3-carbonylhexanoate

: 125971-93-9
(3R,5R)-tert-butyl-6-cyano-3,5-dihydroxyhexanoate

Guidance literature:: With D-glucose; In water; at 28 ℃; for 24 - 48h; Microbiological reaction;

Reference yield: 81.0%

: 773837-37-9
sodium cyanide

: 154026-93-4
1,1-dimethylethyl (3R,5S)-6-chloro-3,5-dihydroxy-4-hexanoate

: 125971-93-9
(3R,5R)-tert-butyl-6-cyano-3,5-dihydroxyhexanoate

Guidance literature:: In water; N,N-dimethyl-formamide; at 20 - 80 ℃; for 2h;

Reference yield: 63.0%

: 143-33-9,25596-52-5
sodium cyanide

: 154026-93-4
1,1-dimethylethyl (3R,5S)-6-chloro-3,5-dihydroxy-4-hexanoate

: 125971-93-9
(3R,5R)-tert-butyl-6-cyano-3,5-dihydroxyhexanoate

Guidance literature:: With halohydrin dehalogenase; In water; at 20 ℃; for 17h; pH=6.7; Product distribution / selectivity; Aqueous phosphate buffer;