Technology Process of 1H-1,3-Diphosphole,
2,3-dihydro-2,2-bis(methylthio)-1,3,4,5-tetraphenyl-, (1R,3R)-rel-
There total 1 articles about 1H-1,3-Diphosphole,
2,3-dihydro-2,2-bis(methylthio)-1,3,4,5-tetraphenyl-, (1R,3R)-rel- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Yield given. Multistep reaction;
1.) -80 deg C, 15 min, 2.) -80 -> 25 deg C;
- Guidance literature:
-
1,3,4,5-tetraphenyl-1,3-diphospholene 2,2-dimethyl thioacetal;
With
dicyclopentadienyltitanium(II) bis(trimethyl phosphite) complex;
In
tetrahydrofuran;
at 20 ℃;
With
water;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
DOI:10.1039/b403436h
- Guidance literature:
-
With
Li; tert-butylchloride;
In
tetrahydrofuran;
A soln. of the starting compd. in THF is stirred at room temp. for 24 h with Li (Ar). To the intermediate tBuCl is added and the mixt. should stand for 24 h. The resulting compd. reacts with the ferrocene compd. at room temp. for 4 h.; Filtn. over silicagel (CH2Cl2), removing of solvent in vacuo, chromy. (silicagel, hexane/CH2Cl2), sublimation (120°C, 1E-1 Torr) or recrystn. from toluene/CH3OH.;
