phenyl N-[(2S)-1-hydroxy-3-methylbutan-2-yl]carbamate

Base Information

Chemical Name:phenyl N-[(2S)-1-hydroxy-3-methylbutan-2-yl]carbamate
CAS No.:126147-71-5
Molecular Formula:C12H17NO3
Molecular Weight:223.272
Hs Code.:
DSSTox Substance ID:DTXSID401195290
Mol file:126147-71-5.mol

Synonyms:126147-71-5;DTXSID401195290;AKOS017808315;Phenyl N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]carbamate

Suppliers and Price of phenyl N-[(2S)-1-hydroxy-3-methylbutan-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of phenyl N-[(2S)-1-hydroxy-3-methylbutan-2-yl]carbamate

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:223.12084340
Heavy Atom Count:16
Complexity:212

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(CO)NC(=O)OC1=CC=CC=C1
Isomeric SMILES:CC(C)[C@@H](CO)NC(=O)OC1=CC=CC=C1

Technology Process of phenyl N-[(2S)-1-hydroxy-3-methylbutan-2-yl]carbamate

There total 3 articles about phenyl N-[(2S)-1-hydroxy-3-methylbutan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 126147-70-4
(2S)-3-Methyl-2-(phenoxycarbonyl)aminobutyric acid

: 126147-71-5
(2S)-3-methyl-2-phenoxycarbonylamino-1-butanol

Guidance literature:: With borane-THF; In tetrahydrofuran; at 0 ℃; for 3h;
DOI:10.1055/s-1989-27337

Reference yield:

: 72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine

: 126147-71-5
(2S)-3-methyl-2-phenoxycarbonylamino-1-butanol

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / KHCO₃, 50percent aq. NaOH / 1.5 h / Ambient temperature

2: 94 percent / BH₃*THF / tetrahydrofuran / 3 h / 0 °C

With sodium hydroxide; borane-THF; potassium hydrogencarbonate; In tetrahydrofuran;
DOI:10.1055/s-1989-27337

Reference yield:

: 1885-14-9
phenyl chloroformate

: 126147-71-5
(2S)-3-methyl-2-phenoxycarbonylamino-1-butanol

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / KHCO₃, 50percent aq. NaOH / 1.5 h / Ambient temperature

2: 94 percent / BH₃*THF / tetrahydrofuran / 3 h / 0 °C

With sodium hydroxide; borane-THF; potassium hydrogencarbonate; In tetrahydrofuran;
DOI:10.1055/s-1989-27337