(+)-dihydropyriculol

Base Information

• Chemical Name: (+)-dihydropyriculol
• CAS No.: 112848-72-3
• Molecular Formula: C₁₄H₁₈O₄
• Molecular Weight: 250.295
• Mol file: 112848-72-3.mol

Synonyms:

Chemical Property of (+)-dihydropyriculol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-dihydropyriculol

There total 3 articles about (+)-dihydropyriculol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1E,3E,5E)-tributylhepta-1,3,5-trienylstannane (1351704-17-0) → (+)-dihydropyriculol (112848-72-3)

Guidance literature:

Multi-step reaction with 3 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane; lithium chloride / N,N-dimethyl-formamide / 36 h / 20 °C

2: lithium aluminium deuteride / tetrahydrofuran / 3 h / -78 °C

3: Magnaporthe grisea, type phytotoxins of rice blast fungus; sucrose; soy sauce / water; ethyl acetate / 24 h / Darkness; Enzymatic reaction

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium aluminium deuteride; trifuran-2-yl-phosphane; lithium chloride; In tetrahydrofuran; water; ethyl acetate; N,N-dimethyl-formamide; 1: Stille coupling;

DOI:10.1002/ejoc.201100771

Reference yield:

2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one (164014-40-8) → (+)-dihydropyriculol (112848-72-3)

Guidance literature:

Multi-step reaction with 3 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane; lithium chloride / N,N-dimethyl-formamide / 36 h / 20 °C

2: lithium aluminium deuteride / tetrahydrofuran / 3 h / -78 °C

3: Magnaporthe grisea, type phytotoxins of rice blast fungus; sucrose; soy sauce / water; ethyl acetate / 24 h / Darkness; Enzymatic reaction

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium aluminium deuteride; trifuran-2-yl-phosphane; lithium chloride; In tetrahydrofuran; water; ethyl acetate; N,N-dimethyl-formamide; 1: Stille coupling;

DOI:10.1002/ejoc.201100771

Reference yield:

(1'E,3'E,5'E)-6-(hepta-1',3',5'-trienyl)-2-hydroxybenzaldehyde-α-d (1351704-15-8) + (1'E,3'E,5'E)-6-(hepta-1',3',5'-trienyl)-2-hydroxybenzenemethanol-α,α,-d2 (1351704-13-6) → C14H17(2)HO4 + (+)-dihydropyriculol (112848-72-3)

Guidance literature:

With Magnaporthe grisea, type phytotoxins of rice blast fungus; sucrose; soy sauce; In water; ethyl acetate; for 24h; Darkness; Enzymatic reaction;

DOI:10.1002/ejoc.201100771

upstream raw materials:

(1'E,3'E,5'E)-6-(hepta-1',3',5'-trienyl)-2-hydroxybenzaldehyde-α-d

(1'E,3'E,5'E)-6-(hepta-1',3',5'-trienyl)-2-hydroxybenzenemethanol-α,α,-d2

(1E,3E,5E)-tributylhepta-1,3,5-trienylstannane

2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one