12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate

Base Information

• Chemical Name: 12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate
• CAS No.: 1609930-01-9
• Molecular Formula: C₅₅H₁₀₂N₂O₆S
• Molecular Weight: 919.491
• Mol file: 1609930-01-9.mol

Synonyms:

Chemical Property of 12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate

There total 5 articles about 12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

10-Undecenal (112-45-8) + tert-butylisonitrile (119072-55-8,7188-38-7) + 3-((12-(cyclohexylamino)-12-oxo-11-(stearoyloxy)dodecyl)thio)propanoic acid (1609930-00-8) → 12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate (1609930-01-9)

Guidance literature:

10-Undecenal; 3-((12-(cyclohexylamino)-12-oxo-11-(stearoyloxy)dodecyl)thio)propanoic acid; In dichloromethane; at 20 ℃; for 0.166667h;

tert-butylisonitrile; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1002/anie.201308960

Reference yield:

Cyclohexyl isocyanide (931-53-3) → 12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate (1609930-01-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dichloromethane / 2 h / 20 °C

2.1: 2,2-dimethoxy-2-phenylacetophenone / 1 h / 20 °C / UV-irradiation

3.1: dichloromethane / 0.17 h / 20 °C

3.2: 12 h / 20 °C

With 2,2-dimethoxy-2-phenylacetophenone; In dichloromethane; 1.1: |Passerini Condensation / 3.1: |Passerini Condensation / 3.2: |Passerini Condensation;

DOI:10.1002/anie.201308960

Reference yield:

10-Undecenal (112-45-8) → 12-((3-((1-(t-butylamino)-1-oxododec-11-en-2-yl)oxy)-3-oxopropyl)thio)-1-(cyclohexylamino)-1-oxododecan-2-yl stearate (1609930-01-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dichloromethane / 2 h / 20 °C

2.1: 2,2-dimethoxy-2-phenylacetophenone / 1 h / 20 °C / UV-irradiation

3.1: dichloromethane / 0.17 h / 20 °C

3.2: 12 h / 20 °C

With 2,2-dimethoxy-2-phenylacetophenone; In dichloromethane; 1.1: |Passerini Condensation / 3.1: |Passerini Condensation / 3.2: |Passerini Condensation;

DOI:10.1002/anie.201308960

upstream raw materials:

Cyclohexyl isocyanide

10-Undecenal

tert-butylisonitrile

3-((12-(cyclohexylamino)-12-oxo-11-(stearoyloxy)dodecyl)thio)propanoic acid

Downstream raw materials:

15-(t-butylcarbamoyl)-31-(cyclohexylcarbamoyl)-17,33-dioxo-16,32-dioxa-4,20-dithiapentacontan-1-oic acid

24-(t-butylcarbamoyl)-41-(cyclohexylamino)-8-(dec-9-en-1-yl)-7,10,26,41-tetraoxo-9,25-dioxa-13,29-dithia-6-azahentetracontan-40-yl stearate

5-((3-((12-(cyclohexylamino)-12-oxo-11-(stearoyloxy)dodecyl)thio)propanoyl)oxy)-2,2-dimethyl-4,19-dioxo-21-(pentylcarbamoyl)-20-oxa-16,32-dithia-3-azapentatriacontan-35-oic acid