Technology Process of benzyl 6-O-tert-butyldiphenylsilyl-2,3-O-isopropylidene-α-D-erythro-hex-4-enopyranoside
There total 9 articles about benzyl 6-O-tert-butyldiphenylsilyl-2,3-O-isopropylidene-α-D-erythro-hex-4-enopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 89 percent / imidazole / dimethylformamide / 6 h / Ambient temperature
2: 97 percent / camphorsulphonic acid / acetone / 16 h / Ambient temperature
3: pyridinium chlorochromate, molecular sieve 3 A / CH2Cl2 / 2 h / Ambient temperature; molecular sieve 3 A
4: sodium borohydride / ethanol / 1 h / 0 °C
5: pyridine / CH2Cl2 / 8 h / -20 °C
6: sodium azide / dimethylformamide / 16 h / Ambient temperature
With
pyridine; 1H-imidazole; sodium tetrahydroborate; sodium azide; 3 A molecular sieve; camphor-10-sulfonic acid; pyridinium chlorochromate;
In
ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)86850-2
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 83 percent / acetyl chloride / 50 deg C for 1.5 h then room temperature for 24 h
2: 89 percent / imidazole / dimethylformamide / 6 h / Ambient temperature
3: 97 percent / camphorsulphonic acid / acetone / 16 h / Ambient temperature
4: pyridinium chlorochromate, molecular sieve 3 A / CH2Cl2 / 2 h / Ambient temperature; molecular sieve 3 A
5: sodium borohydride / ethanol / 1 h / 0 °C
6: pyridine / CH2Cl2 / 8 h / -20 °C
7: sodium azide / dimethylformamide / 16 h / Ambient temperature
With
pyridine; 1H-imidazole; sodium tetrahydroborate; sodium azide; 3 A molecular sieve; camphor-10-sulfonic acid; acetyl chloride; pyridinium chlorochromate;
In
ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)86850-2
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 97 percent / camphorsulphonic acid / acetone / 16 h / Ambient temperature
2: pyridinium chlorochromate, molecular sieve 3 A / CH2Cl2 / 2 h / Ambient temperature; molecular sieve 3 A
3: sodium borohydride / ethanol / 1 h / 0 °C
4: pyridine / CH2Cl2 / 8 h / -20 °C
5: sodium azide / dimethylformamide / 16 h / Ambient temperature
With
pyridine; sodium tetrahydroborate; sodium azide; 3 A molecular sieve; camphor-10-sulfonic acid; pyridinium chlorochromate;
In
ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)86850-2
