C₆₈H₉₄Cl₃N₉O₁₆Si

Base Information

• Chemical Name: C₆₈H₉₄Cl₃N₉O₁₆Si
• CAS No.: 446064-67-1
• Molecular Formula: C₆₈H₉₄Cl₃N₉O₁₆Si
• Molecular Weight: 1427.99
• Mol file: 446064-67-1.mol

Synonyms:

Chemical Property of C₆₈H₉₄Cl₃N₉O₁₆Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₈H₉₄Cl₃N₉O₁₆Si

There total 16 articles about C₆₈H₉₄Cl₃N₉O₁₆Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(E)-(S)-4-((2R,3S)-2-Amino-3-methyl-pentanoylamino)-5-(4-triisopropylsilanyloxy-phenyl)-pent-2-enoic acid allyl ester (446064-66-0) + C58H62Cl3N8O11P (446064-63-7) → C68H94Cl3N9O16Si (446064-67-1)

Guidance literature:

C₅₈H₆₂Cl₃N₈O₁₁P; With ozone;

(E)-(S)-4-((2R,3S)-2-Amino-3-methyl-pentanoylamino)-5-(4-triisopropylsilanyloxy-phenyl)-pent-2-enoic acid allyl ester;

DOI:10.1016/S0040-4039(02)00599-3

Reference yield:

Teoc-aspargine (78221-36-0) → C68H94Cl3N9O16Si (446064-67-1)

Guidance literature:

Multi-step reaction with 6 steps

1: bis(trifluoroacetyl)iodobenzene / pyridine

2: NaOH

3: 88 percent / EDCI; HOBt

4: 100 percent / H₂ / Pd-C

5: EDCI; HOBt

6: 75 percent / O₃

With sodium hydroxide; hydrogen; benzotriazol-1-ol; ozone; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; bis-[(trifluoroacetoxy)iodo]benzene; palladium on activated charcoal; In pyridine; 1: Curtius-degradation;

DOI:10.1016/S0040-4039(02)00599-3

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C68H94Cl3N9O16Si (446064-67-1)

Guidance literature:

Multi-step reaction with 5 steps

1: NaOH

2: 88 percent / EDCI; HOBt

3: 100 percent / H₂ / Pd-C

4: EDCI; HOBt

5: 75 percent / O₃

With sodium hydroxide; hydrogen; benzotriazol-1-ol; ozone; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal;

DOI:10.1016/S0040-4039(02)00599-3

upstream raw materials:

(E)-(S)-4-((2R,3S)-2-Amino-3-methyl-pentanoylamino)-5-(4-triisopropylsilanyloxy-phenyl)-pent-2-enoic acid allyl ester

C₅₈H₆₂Cl₃N₈O₁₁P

di-tert-butyl dicarbonate

Teoc-aspargine

Downstream raw materials:

C₆₅H₉₀Cl₃N₉O₁₆Si