3-Methyl-beta-styrylboronic acid pinacol ester, 97%

Base Information

• Chemical Name: 3-Methyl-beta-styrylboronic acid pinacol ester, 97%
• CAS No.: 1315277-67-8
• Molecular Formula: C₁₅H₂₁BO₂
• Molecular Weight: 244.142
• Mol file: 1315277-67-8.mol

Synonyms:

Chemical Property of 3-Methyl-beta-styrylboronic acid pinacol ester, 97%

Chemical Property:

Purity/Quality:

2-[2-(3-Methylphenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Methyl-beta-styrylboronic acid pinacol ester, 97%

There total 15 articles about 3-Methyl-beta-styrylboronic acid pinacol ester, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-ethynyl-3-methyl-benzene (766-82-5) + bis(pinacol)diborane (73183-34-3) → (E)-4,4,5,5-tetramethyl-2-(3-methylstyryl)-1,3-dioxa-2-borolane (1421061-31-5,1315277-67-8)

Guidance literature:

With sodium methylate; copper; In ethanol; at 25 ℃; for 24h; regioselective reaction; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1039/c3cc48670b

Reference yield: 87.0%

1-ethynyl-3-methyl-benzene (766-82-5) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → (E)-4,4,5,5-tetramethyl-2-(3-methylstyryl)-1,3-dioxa-2-borolane (1421061-31-5,1315277-67-8)

Guidance literature:

With (1,3-bis(2,6-di-iso-propylphenyl)-4,5-dihydroimidazol-2-ylidene) copper chloride; tris-tert-butylphosphinimide, lithium salt; In benzene; at 20 ℃; for 13h; stereoselective reaction; Glovebox; Inert atmosphere;

DOI:10.1016/j.tetlet.2017.03.011

Reference yield: 87.0%

1-ethynyl-3-methyl-benzene (766-82-5) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-(2-m-tolylvinyl)[1,3,2]dioxaborolane (1315277-67-8)

Guidance literature:

With C₃₉H₆₅CuN₃P; In benzene; at 20 ℃; for 13h;

upstream raw materials:

1-ethynyl-3-methyl-benzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

bis(pinacol)diborane

3-(3-methylphenyl)prop-2-ynoic acid

Downstream raw materials:

(E)-1-(2-iodovinyl)-3-methylbenzene